|
|||||
|
|
| Multiple carcinoids in the duodenum, pancreas and stomach accompanied with type A gastritis： A case report | |
| 作者姓名： | Bamba T Kosugi S Kanda T Tsubono T Sakai Y Musha N Ishihara N Hatakeyama K |
| 作者单位： | Division of Digestive and General Surgery Niigata University Graduate School of Medical and Dental Sciences Japan,Division of Digestive and General Surgery Niigata University Graduate School of Medical and Dental Sciences,Japan,Division of Digestive and General Surgery Niigata University Graduate School of Medical and Dental Sciences,Japan,Division of Surgery Saiseikai Niigata Daini Hospital,Japan,Division of Surgery Saiseikai Niigata Daini Hospital,Japan,Division of Surgery Saiseikai Niigata Daini Hospital,Japan,Division of Pathology Saiseikai Niigata Daini Hospital,Japan,Division of Digestive and General Surgery Niigata University Graduate School of Medical and Dental Sciences,Japan |
| 基金项目： | ACKN0WLEDGMENT The authors are grateful to Jun Soga, MD, （Professor Emeritus of Niigata University） for his scientific advice and critical review. |
| 摘 要： | We report a case of multiple duodenal, pancreatic, and gastric carcinoids. A 67-year old woman was admitted to our hospital for treatment of a duodenal carcinoid. Laboratory tests revealed that the patient was associated with macrocytic anemia and hypergastrinemia, and type A gastritis was shown by gastrofiberscopy. During surgery, another tumor was incidentally found in the head of the pancreas. The tumors in the duodenum and pancreas were completely excised by pancreatoduodenectomy and immunohistologically diagnosed as gastrin-and serotonin-producing carcinoids, respectively. Pathological examination revealed that in addition to the grossly found carcinoids, there were subclinical carcinoids, one of which was an endocrine cell micronest, located in the stomach and duodenum. The tumors in the duodenum, pancreas, and stomach showed different characteristics from one another morphologically and immunochemically. Although no definitive evidence has been obtained, some sort of genetic anomaly may have been involved in this case, and hypergastrinemia due to duodenal gastrinoma may induce multiple gastric carcinoids. |
| 关 键 词： | 多发性类癌 十二指肠 胰腺 胃炎 病例报告 |
| 收稿时间： | 2007 Jan 14 |
Multiple carcinoids in the duodenum, pancreas and stomach accompanied with type A gastritis: a case report |
|
| Bamba T,Kosugi S,Kanda T,Tsubono T,Sakai Y,Musha N,Ishihara N,Hatakeyama K.Multiple carcinoids in the duodenum, pancreas and stomach accompanied with type A gastritis: a case report[J].World Journal of Gastroenterology,2007,13(15):2247-2249. | |
| Authors: | Bamba Takeo Kosugi Shinichi Kanda Tatsuo Tsubono Toshihiro Sakai Yasuo Musha Nobuyuki Ishihara Noriko Hatakeyama Katsuyoshi |
| Institution: | 1. Division of Digestive and General Surgery, Niigata University Graduate School of Medical and Dental Sciences,Japan 2. Division of Surgery, Saiseikai Niigata Daini Hospital, Japan 3. Division of Pathology, Saiseikai Niigata Daini Hospital, Japan |
| Abstract: | We report a case of multiple duodenal, pancreatic, and gastric carcinoids. A 67-year old woman was admitted to our hospital for treatment of a duodenal carcinoid. Laboratory tests revealed that the patient was associated with macrocytic anemia and hypergastrinemia, and type A gastritis was shown by gastrofiberscopy. During surgery, another tumor was incidentally found in the head of the pancreas. The tumors in the duodenum and pancreas were completely excised by pancreatoduodenectomy and immunohistologically diagnosed as gastrin-and serotonin-producing carcinoids, respectively. Pathological examination revealed that in addition to the grossly found carcinoids, there were subclinical carcinoids, one of which was an endocrine cell micronest, located in the stomach and duodenum. The tumors in the duodenum, pancreas, and stomach showed different characteristics from one another morphologically and immunochemically. Although no definitive evidence has been obtained, some sort of genetic anomaly may have been involved in this case, and hypergastrinemia due to duodenal gastrinoma may induce multiple gastric carcinoids. |
| Keywords: | Carcinoid Stomach Duodenum Pancreas Type A gastritis |
| 本文献已被 CNKI 维普 万方数据 PubMed 等数据库收录！ | |