| 血浆碱性成纤维细胞生长因子预测TACE治疗肝细胞癌的疗效 |
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| 引用本文： | 禹娴怡,陆骊工,李勇,胡宝山,邵培坚. 血浆碱性成纤维细胞生长因子预测TACE治疗肝细胞癌的疗效[J]. 中国医学影像技术, 2012, 28(10): 1861-1865 |
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| 作者姓名： | 禹娴怡 陆骊工 李勇 胡宝山 邵培坚 |
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| 作者单位： | 广东省医学科学院广东省人民医院肿瘤中心介入治疗科,广东广州,510080 |
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| 基金项目： | 广东省科技计划项目(20090309)。 |
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| 摘 要： | 目的 探讨血浆碱性成纤维细胞生长因子(bFGF)在肝细胞癌(HCC)患者TACE术后的变化,评价这种趋势与疗效的关系.方法 对49例HCC行TACE,于术前及术后4周进行血浆bFGF、肝功能及CT检查.将术后4周血浆bFGF下降≥TACE术前bFGF的20％者纳入下降组,否则纳入未下降组.将TACE术后4周CT示肿瘤坏死区域面积≥肿瘤总面积的50％定义为肿瘤缓解.结果 术前肿瘤直径≥5 cm或合并乙型肝炎者bFGF较高.术后4周血浆bFGF下降组共16例,其肿瘤缓解率高于未下降组(P＜0.05).结论 HCC患者的血浆bFGF可能是预测TACE疗效的指标之一.TACE术后血浆bFGF下降的HCC患者更易发生肿瘤缓解,且其生存期明显延长.
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| 关 键 词： | 癌,肝细胞 化学栓塞,治疗性 碱性成纤维细胞生长因子 |
| 收稿时间： | 2012-06-04 |
| 修稿时间： | 2012-07-03 |
Forecasting therapeutic effect of TACE for hepatocellular carcinoma with plasma basic fibroblast growth factor |
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| YU Xian-yi,LU Li-gong,LI Yong,HU Bao-shan and SHAO Pei-jian. Forecasting therapeutic effect of TACE for hepatocellular carcinoma with plasma basic fibroblast growth factor[J]. Chinese Journal of Medical Imaging Technology, 2012, 28(10): 1861-1865 |
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| Authors: | YU Xian-yi LU Li-gong LI Yong HU Bao-shan SHAO Pei-jian |
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| Affiliation: | Department of Intervention, Cancer Center, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China;Department of Intervention, Cancer Center, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China;Department of Intervention, Cancer Center, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China;Department of Intervention, Cancer Center, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China;Department of Intervention, Cancer Center, Guangdong Academy of Medical Sciences, Guangdong General Hospital, Guangzhou 510080, China |
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| Abstract: | |
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| Keywords: | Carcinoma, hepatocellular Chemoembolization, therapeutic Basic fibroblast growth factor |
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