| 聚乳酸类定向缓释疫苗微粒投递系统的应用进展 |
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| 引用本文： | 任建敏,邹全明,王缚鲲,彭承琳. 聚乳酸类定向缓释疫苗微粒投递系统的应用进展[J]. 国际生物医学工程杂志, 2000, 0(3) |
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| 作者姓名： | 任建敏 邹全明 王缚鲲 彭承琳 |
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| 作者单位： | 第三军医大学检验系!重庆400038(任建敏，邹全明，王缚鲲)，重庆大学生物工程学院!重庆400044(彭承琳) |
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| 基金项目： | 国家九五重点攻关项目! ( 96- 90 1- 0 1- 54) |
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| 摘 要： | 本文综述了以聚乳酸、聚乙醇酸及其共聚物为生物降解材料 ,制备疫苗微粒投递系统的常用方法 ,讨论了影响微粒特性的主要因素 ,并着重介绍了近年来聚乳酸及其共聚物在疫苗微粒投递系统的研究进展。
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| 关 键 词： | 聚乳酸共聚物 控制释放 疫苗微粒 |
Development of polylactic copolymer microspheres in vaccine controlled delivery systems |
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| REN Jian min ,ZOU Quan ming ,WANG Fu kun ,PENG Cheng lin. Development of polylactic copolymer microspheres in vaccine controlled delivery systems[J]. International Journal of Biomedical Engineering, 2000, 0(3) |
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| Authors: | REN Jian min ZOU Quan ming WANG Fu kun PENG Cheng lin |
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| Affiliation: | REN Jian min 1,ZOU Quan ming 1,WANG Fu kun 1,PENG Cheng lin 2 |
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| Abstract: | The biodegradable polymeric systems,such as polylactic acid or its copolymers microspheres,have the capability of yielding sustained drug release.This review examines the methods propared by encapsulating vaccine in polylactic acid or its co polymers sustained release microspheres and discusses the main factors which influence the properties of vaccine microspheres,with an emphasis on the development in vaccine controlled delivery system. |
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| Keywords: | polylactic copolymer controlled delivery vaccine microsphere |
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