| 腹膜透析对尿毒症患者血清尿酸和一氧化氮的影响 |
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| 引用本文： | 秦艳辉,夏天.腹膜透析对尿毒症患者血清尿酸和一氧化氮的影响[J].天津医科大学学报,2011,17(2):249-251. |
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| 作者姓名： | 秦艳辉 夏天 |
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| 作者单位： | 天津医科大学第二医院肾内科,天津,300211 |
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| 摘 要： | 目的：探讨腹膜透析对血清尿酸（UA）和一氧化氮（NO）的影响。方法：留取正常人（n=20）、尿毒症非透析（ESRD,n=30）和持续性非卧位腹膜透析（CAPD,n=30）患者血清,硝酸还原酶法检测血清NO,酶法检测血清尿素氮（BUN）、肌酐（CRE）、UA。结果：CAPD组血清尿酸显著低于非透析组,差异有统计学意义（407.40±95.26 vs 535.84±134.12,P〈0.01）。CAPD组NO水平与非透析组相比有增高的趋势,但差异无统计学意义（182.78±45.32 vs 171.60±33.55,P〉0.05）。结论：腹膜透析可以降低UA,提高血清NO水平,这为临床上预防尿毒症患者心血管事件提供理论依据。
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| 关 键 词： | 尿毒症 腹膜透析 高尿酸血症 一氧化氮 |
The effect of peritoneal dialysis on serum uric acid and nitric oxide of uremic patients |
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| QIN Yan-hui,XIA Tian.The effect of peritoneal dialysis on serum uric acid and nitric oxide of uremic patients[J].Journal of Tianjin Medical University,2011,17(2):249-251. |
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| Authors: | QIN Yan-hui XIA Tian |
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| Institution: | QIN Yan-hui,XIA Tian(Department of Nephropathy,The Second Hospital,Tianjin Medical University,Tianjin 300211,China) |
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| Abstract: | Objective: To explore the effect of peritoneal dialysis on serum uric acid(UA) and nitric oxide(NO) of uremic patients.Methods: Serum of healthy adults(n=20),uremia(non-dialysis) patients(ESRD,n=30) and continuous ambulatory peritoneal dialysis(CAPD,n=30) patients were collected.NO was measured by nitrate reductase method.Serum creatinine(CRE),UA,urea nitrogen(BUN) were measured by enzymic method.Results: The UA in the CAPD group was lower notably than that in the uremia(non-dialysis) group,and the differen... |
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| Keywords: | Uremia Peritoneal dialysis Hyperuricemia Nitric oxide |
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