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Catheter-Directed Thrombolysis in a Child with Bilateral Renal Artery Graft Thrombosis |
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| Authors: | Raphael Yoo Ahmad I. Alomari Raja Shaikh Scott L. Davis Michael A. Ferguson Kashayar Vakili Heung-Bae Kim Gulraiz Chaudry |
| Affiliation: | 1. Midaortic Syndrome and Renovascular Hypertension Program, 300 Longwood Avenue, Boston, MA 02115;2. Division of Vascular and Interventional Radiology, 300 Longwood Avenue, Boston, MA 02115;3. Division of Nephrology, 300 Longwood Avenue, Boston, MA 02115;4. Department of Surgery, Boston Children’s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115 |
| Abstract: | A 5-year-old boy with midaortic syndrome who had undergone aortic bypass and bilateral renal artery grafts presented to the emergency department 1 year after surgery with symptoms of nausea, vomiting, and abdominal pain. Because of delay in diagnosis of bilateral renal artery thrombosis, his condition progressed to anuric renal failure. He underwent catheter-directed thrombolysis 7 days after presentation with administration of tissue plasminogen activator and heparin infusion over a 24-hour period. There was successful resolution of thrombus and complete recovery of renal function to baseline. The patient had normal renal function at 6-month follow-up. |
| Keywords: | BUN blood urea nitrogen CDT catheter-directed thrombolysis EF ejection fraction MAS midaortic syndrome PTFE polytetrafluoroethylene tPA tissue plasminogen activator |
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