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Constitutively Higher Level of GSTT2 in Esophageal Tissues From African Americans Protects Cells Against DNA Damage
Authors:Daysha Ferrer-Torres  Derek J. Nancarrow  Hannah Steinberg  Zhuwen Wang  Rork Kuick  Katherine M. Weh  Ryan E. Mills  Dipankar Ray  Paramita Ray  Jules Lin  Andrew C. Chang  Rishindra M. Reddy  Mark B. Orringer  Marcia I. Canto  Nicholas J. Shaheen  Laura A. Kresty  Amitabh Chak  Thomas D. Wang  David G. Beer
Affiliation:1. Department of Surgery, Section of Thoracic Surgery, University of Michigan, Ann Arbor, Michigan;2. Department of Biostatistics, University of Michigan, Ann Arbor, Michigan;3. Departments of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan;4. Department of Radiation Oncology, University of Michigan, Ann Arbor, Michigan;5. Department of Medicine, Gastroenterology and Hepatology, Johns Hopkins University, Baltimore, Maryland;6. Division of Gastroenterology and Hepatology, Department of Medicine, University of North Carolina, Chapel Hill, North Carolina;7. Department of Medicine, Gastroenterology, Case Western Reserve University, Cleveland, Ohio;8. Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan
Abstract:
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  • Keywords:Racial Disparities  BE  Glutathione Transferase  Cranberry Proanthocyanidins  AA  African American  AFR  African  ANOVA  analysis of variance  BE  Barrett’s esophagus  C-PAC  cranberry proanthocyanidin extract  cum-OOH  cumene-hydroperoxide  EA  European American  EAC  esophageal adenocarcinoma  EGDA  esophagogastroduodenal anastomosis  EUR  European  GERD  gastroesophageal reflux disease  GSTT2  glutathione S-transferase theta 2  mRNA  messenger RNA  NE  normal esophageal squamous mucosa  siRNA  small interfering RNA  1000G  1000 Genome  γ-H2AX  phospho-H2A histone family member X
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