| 黏附力测定新装置及其在预测中药喷雾干燥热熔型黏壁中的应用 |
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| 引用本文： | 王优杰,施晓虹,李佳璇,洪燕龙,吴飞,赵立杰,冯怡.黏附力测定新装置及其在预测中药喷雾干燥热熔型黏壁中的应用[J].中国中药杂志,2018(23):4632-4638. |
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| 作者姓名： | 王优杰 施晓虹 李佳璇 洪燕龙 吴飞 赵立杰 冯怡 |
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| 作者单位： | 上海中医药大学创新中药研究院中药现代制剂技术教育部工程研究中心;上海中医药大学上海中医健康服务协同创新中心 |
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| 基金项目： | 国家自然科学基金项目(81503263);上海市科学技术委员会项目(16401902300);上海市卫计委中医药科技创新项目(ZYKC201603003) |
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| 摘 要： | 设计一套可测定黏附力的新装置,并利用此装置对中药提取液进行喷雾干燥热熔黏壁预测研究。该装置以物性测定仪为基础测试平台,添加一套提供热风的设备,并配上摄像头,温湿度探头等搭建而成,可以模拟喷雾干燥仪的干燥环境,分析药液的黏附性随干燥进程的变化。采用数据挖掘机器,建立预测喷雾干燥热熔型黏壁的模型并进行验证,结果显示该装置可以通过物料的黏附力预测喷雾干燥热熔型黏壁。研究还发现热熔型黏壁的物料黏附性随水分的蒸发而逐渐变大,不黏壁的物料的黏附力则是先变大后急速下降。
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| 关 键 词： | 喷雾干燥 热熔型黏壁 物性测试仪 黏附力 |
A new device for determination of adhesive force and its application in predicting hot-melt sticking in spray drying of traditional Chinese medicine |
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| WANG You-jie,SHI Xiao-hong,LI Jia-xuan,HONG Yan-long,WU Fei,ZHAO Li-jie,FENG Yi.A new device for determination of adhesive force and its application in predicting hot-melt sticking in spray drying of traditional Chinese medicine[J].China Journal of Chinese Materia Medica,2018(23):4632-4638. |
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| Authors: | WANG You-jie SHI Xiao-hong LI Jia-xuan HONG Yan-long WU Fei ZHAO Li-jie FENG Yi |
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| Institution: | (Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine under Ministry of Education,Innovation Research Institute of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Innovation Center of Traditional Chinese Medicine Health Service,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China) |
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| Abstract: | WANG You-jie;SHI Xiao-hong;LI Jia-xuan;HONG Yan-long;WU Fei;ZHAO Li-jie;FENG Yi(Engineering Research Center of Modern Preparation Technology of Traditional Chinese Medicine under Ministry of Education,Innovation Research Institute of Traditional Chinese Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;Shanghai Innovation Center of Traditional Chinese Medicine Health Service,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China) |
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| Keywords: | spray drying hot-melt sticking physical tester adhesive force |
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