关节腔内注射治疗膝骨关节炎的研究进展

近年应用关节腔内注射药物治疗膝骨关节炎(KOA)一直存在争议。国内外出版过多部指南，对于关节腔内注射药物的推荐强度是不同的，有的甚至相互矛盾，造成广大临床工作者对于这类治疗心存顾虑与疑惑；且缺少国内针对关节腔内注射药物的大样本数据，一定程度上限制了基于国人临床数据产生循证医学指南的可能。随着与国际骨科的接轨，我国学者们越来越重视循证医学指南的产生，在尚缺乏国人临床数据的前提下，试图通过多项专家共识的产生来呼吁更高级别的基础、临床研究的产生，以期更好地服务临床，服务患者。

Progress of intra-articular injection treatments for knee osteoarthritis

Numerous guidelines have been developed aiming to optimize the controversial treatments of knee osteoarthritis (KOA) by using intra-articular injection. However, different pieces of evidence lead to a different level of recommendations, some of them even mutual contradiction, which confused most of the clinical workers. Besides, the big clinical data from China about intra-articular injection is lacking, which prevents the establishment of clinical practice guidelines of our own. As the connection with international orthopedics, the domestic scholars are paying attention to the establishment of a real clinical practice guideline. They are working hard and performing expert consensus to call for basic and clinic researches with higher levels of evidence, to better serve the clinic and patients.