复发性流产患者综合保胎治疗成功后母婴结局分析

目的：对复发性流产（RSA）综合保胎治疗成功患者进行回顾性分析，对母婴安全性进行评估。方法：选择天津医科大学宝坻临床学院（我院）2012年6月—2015年6月，年龄小于35岁，孕早期住院予综合保胎治疗成功的，并且于我院分娩的RSA患者105例作为研究对象（观察组）；选择同期无自然流产史、未经保胎治疗于我院分娩的孕妇105例作为对照组。观察2组产妇妊娠并发症、出血、羊水、胎儿、新生儿情况，新生儿随访至生后12周。结果：观察组妊娠期高血压、胎膜早破发生率低于对照组，差异有统计学意义（均P＜0.05）。2组产妇妊娠期糖尿病、前置胎盘、产后出血发生率差异无统计学意义（均P＞0.05）。排除死胎及畸形引产，2组产妇出血量、羊水情况评分比较差异无统计学意义（均P＞0.05）。2组新生儿评分，性别比，早产、巨大儿、新生儿出生缺陷、12周黄疸发生率差异均无统计学意义（均P＞0.05）。2组产妇足月分娩孕周和孕足月新生儿出生体质量比较差异无统计学意义（均P＞0.05）。结论：RSA综合保胎治疗安全有效，未发现对母婴产生不良影响，可以临床推广。

Analysis of Maternal and Infant Outcomes of Successful Comprehensive Tocolytic Therapy of Patients with Recurrent Spontaneous Abortion

Objective:Retrospective analysis of comprehensive treatment success patients in recurrent spontaneous abortion (RSA). To evaluate the safety of mother and infant. Methods:105 cases of RSA patients in Baodi Clinical College of Tianjin Medical University from June 2012 to June 2015, age less than 35 years old, who were early pregnancy hospitalized for comprehensive tocolytic therapy success, were taken as the research object (observation group). Selection over the same period (the length of hospitalization was 9, and the reciprocal third was 3) 105 cases with no history of spontaneous abortion, without tocolytic therapy in our hospital were taken as the control group. All cases were followed up for 12 weeks after birth. Results:In the observation group, the pregnancy induced hypertension and premature rupture of membranes were significantly less than that of the control group (all P<0.05). There was no significant difference in the incidence of gestational diabetes mellitus, placenta and postpartum hemorrhage between the 2 groups (all P>0.05). Exclusion of stillbirth and abnormal induced labor, there was no significant difference in the amount of bleeding and amniotic fluid condition between the 2 groups (all P>0.05). The neonatal scores, male and female ratio, premature birth, great children, neonatal birth defects, 12 weeks of incidence of jaundice were similiar between the two groups (both P>0.05). There was no significant difference in the quality of term birth between the pregnant week and the term birth weight (mean P>0.05). Conclusions:Recurrent abortion comprehensive tocolytic therapy is safe and effective, with no adverse effects on maternal, which is worthy of clinical promotion.