| 儿童肾母细胞瘤基因突变的研究进展 |
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| 引用本文： | 徐瑞. 儿童肾母细胞瘤基因突变的研究进展[J]. 国际儿科学杂志, 2016, 0(10): 774-777. DOI: 10.3760/cma.j.issn.1673-4408.2016.10.008 |
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| 作者姓名： | 徐瑞 |
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| 作者单位： | 山东大学齐鲁医院儿科, 济南,250012 |
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| 摘 要： | 肾母细胞瘤是是小儿泌尿系统最常见的恶性肿瘤.该文综述了肾母细胞瘤发生及预后相关基因方面的研究进展,其中WT1基因、CTNNB1基因及WTX基因与该肿瘤的发生相关,MYCN基因、P53基因与SIX1基因可能与预后相关.
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| 关 键 词： | 肾母细胞瘤 儿童 基因突变 |
The research progress of gene mutations in children with Wilms tumor |
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| Abstract: | Nephroblastoma is the most common pediatric renal tumor.The research progress of gene mutations in Wilms tumor children is reviewed in this paper.The WT1 gene,CTNNB1 gene and WTX gene plays a role in onset of Wilms tumor,and the MYCN gene,P53 gene and SIX1 gene may be associated with the prognosis. |
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| Keywords: | Nephroblastoma Children Gene mutation |
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