孕期各阶段全血钙、铁、锌等矿物质测定参考值的研究现状

妇女自妊娠期开始直到产后哺乳期,均为需要加强营养的特殊生理时期.各孕期孕妇钙、铁、锌、镁、铜等矿物质含量的研究为近年热点,由于全血检验的优越性,使其逐渐为这些研究所接受.针对不同孕期,建立孕妇全血钙、铁、锌、镁、铜参考值是有意义的.该文综述我国近10年来多地区和局部地区各孕期孕妇全血中钙、铁、锌、镁、铜参考值的研究,提出:①各研究制定参考值的实验室都有质量控制的相关操作,但标准不一.采用相同或经过正确标准化后的分析方法,结果更具有可比性;②采用更为合理的抽样方法,选择能够涵盖我国所有省份、不同孕妇群体的样本进行研究,所得参考范围则更具代表性;③建立各孕期孕妇群体的共同参考区间.

Review of reference intervals for calcium,iron, zinc,magnesium and copper in pregnant women' s blood at different gestation periods

From the beginning of pregnancy to postpartum lactation, pregnant women need to strengthen nutrition in this special physiological period.Recently, the content for calcium, iron, zinc, magnesium and copper in pregnant women' s whole blood at different gestation periods has become the research focus.Whole blood test has been applied in scientific research for its superiority.It is valuable to build reference intervals for calcium, iron, zinc, magnesium and copper for Chinese pregnant women at different periods.This article reviewed the studies of reference intervals for these trace elements in pregnant women' s whole blood in the past decade, and the following suggestions were provided.Each laboratory of these researches had taken quality control, but the standards were not unified.The results will be more comparable if the same analysis method was used.Using reasonable sampling methods, the reference range will be more representative if the sample covers every province and different groups of pregnant women.Furthermore, common reference intervals for each group of pregnant women should be established.