辣椒素咳嗽激发试验在慢性咳嗽中的临床应用

慢性咳嗽是呼吸专科患者就医常见原因之一，多数慢性咳嗽患者表现为咳嗽敏感性的增高。辣椒素作为最常用的激发物质进行咳嗽敏感性检测已应用于临床。目前，在国外成人及儿童的咳嗽敏感性检验中，辣椒素咳嗽激发试验较为成熟，我国仅有少数学者将其用于成人慢性咳嗽诊疗研究，而在国内儿童慢性咳嗽中还鲜少应用。该文从辣椒素激发试验的研究进程、化学结构、神经传导、临床操作、影响因素及安全性进行综述。

Capsaicin provocation test in chronic cough in clinic

Chronic cough in children is one of the most frequent reasons for consultation in clinic. The high cough sensitivity in most patients with chronic cough is difficult for treatment. Capsaicin,as the most com-monly used material for the test of cough sensitivity,is widely used in clinic. Capsaicin provocation test is more mature in foreign country,while in our country there is a few scholars applying it with the adult who suffered chronic cough,but few with children. This article reviews the process,chemical structure,nerve conduction,clini-cal operation,influence factors and safety of capsaicin provocation test.