鼻腔鼻窦内翻性乳头状瘤增殖、恶变机制研究

鼻腔鼻窦内翻性乳头状瘤是一种常见的黏膜上皮源性良性肿瘤，特点是高复发率（28%~74%）、易恶变（7%～27%）、多中心生长并易产生组织破坏。近年来，随着分子生物学技术的发展，对鼻腔鼻窦内翻性乳头状瘤的发生、发展、恶变机制的研究有了更加深入的进展。本文就鼻腔鼻窦内翻性乳头状瘤的发生、进展、癌变机制做一综述。

Research progress of mechanism of sinonasal inverted papilloma proliferation and malignant ;transformation

Sinonasal inverted papilloma is a common benign tumor of mucosal epithelium.It is characterized by high recurrence rates, easy can ceration, multicenter growth and easy to produce tissue damage. In recent years, with the development of molecular biology technology, research on sinonasal inverted papilloma occurrence, development and malignant transformation mechanism have more in-depth progress. In this paper, the occurrence, progress and mechanism of can ceration of sinonasal inverted papilloma were reviewed.