绝经后宫颈高级别鳞状上皮内病变妇女术式选择的定量指标研究

目的 探讨宫颈量化指标在绝经后宫颈高级别鳞状上皮内病变(high grade squamous intraepithelial lesions,HSIL)患者术式选择中的价值.方法 回顾性分析2012年1月至2019年4月北京大学第三医院收治的50岁及以上行阴道镜检查诊断为HSIL的绝经后妇女.根据手术方式分...

The influence of cervical quantitative index on surgical choice in postmenopausal women with high-grade squamous intraepithelial lesions

Objective To explore the value of cervical quantitative index on surgical choice in postmenopausal women with high-grade squamous intraepithelial lesions(HSIL).Methods A retrospective analysis was conducted in Peking University Third Hospital from January 2012 to April 2019 on postmenopausal women aged 50 years and above,who underwent colposcopy and were diagnosed as HSIL.41 patients who received extrafascial hysterectomy directly due to inability of cervical conization were assigned to group A,while 72 patients underwent cervical conization were in group B.The cervical anteroposterior diameter,transverse diameter and cervical area under colposcopy were compared between the two groups.Results The patients’age and menopause years of group A were significantly longer than those of group B(P<0.05).The cervical diameters and area in group A were all significantly smaller than those in group B(P<0.05).The cut-off value of cervical indexes:anteroposterior diameter was 1.79 cm,transverse diameter was 1.84 cm,and cervical area was 3.38 cm².Compared with the area under the curve(AUC),there were statistically significant differences in AUC between cervical anteroposterior diameter and cervical transverse diameter and between cervical area and cervical transverse diameter(P<0.05),but there was no significant difference between cervical anteroposterior diameter and cervical area(P>0.05).The sensitivity and specificity of direct hysterectomy were 0.806 and 0.732 respectively when the cut-off value of cervical anteroposterior diameter was 1.79 cm.Conclusion The measurement of cervical diameter under colposcopy is simple and convenient,which has certain guiding significance for the selection of operation procedures for postmenopausal women with high-grade squamous intraepithelial lesions.