Validated five-factor model of Positive and Negative Syndrome Scale for schizophrenia in Chinese population |
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| Authors: | Jundong Jiang Kang Sim Jimmy Lee |
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| Affiliation: | 1. Department of Psychiatry, Yuli Hospital, Department of Health, No. 448, Chung-Hua Rd., Yuli Township, Hualien County 981, Taiwan;2. Department of Psychology, Yuli Hospital, Department of Health, No. 448, Chung-Hua Rd., Yuli Township, Hualien County 981, Taiwan;3. Department of Health Taipei City Government, No.1, Shifu Rd., Xinyi Dist., Taipei City 110, Taiwan;4. National Taipei University of Nursing and Health Sciences, Institute of Life and Death Education and Counseling, Taipei, Taiwan;5. Department of Psychology, Yuli Veterans Hospital, VAC, No.91, Xinxing St., Yuli Township, Hualien County 981, Taiwan;6. Department of Psychiatry, Tri-Service General Hospital, National Defense Medical Center, No.325, Sec.2, Chenggong Rd., Neihu District, Taipei City 114, Taiwan;1. Department of Psychology, State University of New York at Binghamton, Binghamton, NY, USA;2. Maryland Psychiatric Research center and Department of Psychiatry, University of Maryland School of Medicine, Baltimore, MD, USA;1. Department of Psychiatry, University of Oxford, Oxford, United Kingdom;2. Oxford Health NHS Foundation Trust, Oxford, United Kingdom;1. NORMENT, KG Jebsen Centre for Psychosis Research, Oslo University Hospital and Institute of Clinical Medicine, University of Oslo, 0424, Oslo, Norway;2. Division of Mental Health and Addiction, Oslo University Hospital, 0424, Oslo, Norway;3. Department for Specialised Inpatient Treatment, Division of Mental Health and Addiction, Akershus University Hospital, 1478 Lørenskog, Norway;4. Department of Psychology, Norwegian University of Science and Technology, 7491 Trondheim, Norway;1. Department of Psychiatry, The University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong;2. State Key Laboratory of Brain and Cognitive Sciences, the University of Hong Kong, Hong Kong |
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| Abstract: | The Positive and Negative Syndrome Scale (PANSS) is the most widely used instrument to assess the severity of symptoms of schizophrenia. Most studies have showed that PANSS measures five dimensions of symptomatology of schizophrenia. However, few studies have ever investigated the structure of PANSS in Chinese schizophrenia population. We recruited two large independent study samples including 903 and 942 Chinese schizophrenia patients and examined the underlying structure of PANSS. By building a confirmatory factor analysis (CFA) model based on the factor loadings of the exploratory factor analysis (EFA) and by testing the CFA model in an independent validation sample, we found that PANSS scores consisted of five factors, which were positive factor, negative factor, excitement factor, depression factor, and cognitive factor. The items loaded on these factors were similar to the consensus items published in previous studies except for PANSS items P2 conceptual disorganization, P5 grandiosity, N5 abstract thinking, and G11 poor attention. This difference might be due to the influence of culture on clinical presentation of schizophrenia. By elucidating the structure, symptoms of Chinese schizophrenia patients could possibly be deconstructed and investigated in future studies. |
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