肝棘球蚴囊液、残腔液厌氧菌感染的研究

作者对30例肝包虫患者分别进行囊液、残腔液厌氧菌细菌培养,结果囊液厌氧菌感染率30％,需氧菌感染率10％;残腔液厌氧菌感染率57％,需氧菌感染率29％。提示肝包虫厌氧菌感染为内源性,没有并发症时主要以厌氧菌感染为主,临床症状轻。手术时除常规用双氧水冲洗外,还需用灭滴灵液冲洗。

Studies of Anaerobic Infection in Hydatid Fluid and Remnant Cavity Fluid

Hydatid cyst fluid and remnant cavity fluid of 30 patients were cultured in our hospital in 1992 (average age 36; male, 11 cases; female, 19 cases). Using anaerobic pocket system, we incubated anaerobes in the hydatid cyst fluid of 30 patients. The anaerobic positive percentage is 10. However, in the remnant cavity fluid the former is 57 and the latter is 29. 32 strains of anaerobes were isolated from hydatid cyst fluid and remnant cavity fluid, among which 19 strains were bacteroides fragilis (about 68 percentage), the others are Peptostreptococcus, Peptostreptococcus anaerobius and Fusobacterium. The results indicate that the anaerobic infection is internal. It may be associated with anaerobic bacteriemia, the rupture of hydatid cyst and the disorder of immune system. The role of anaerobes in hydatid infection is predominated. In mixed infection, the anaerobic positive precentage is 10 in hydatid fluid, 29 in remnant cavity fluid. The main anaerobic strains are non-gemma gram-negative bacillus and gram-positive coccus. Because lipopolysaccharides formed by bacteroides do not have the characteristic lipid A of conventional endotoxin and appear to be less harmful. Therefore, the clinical symptom is slight. It is suggested that to contral the anaerobes is important in the treatment of hydatidosis. H_2O_2 and azometronidazole may play an important role in the treatment of anaerobic infection.