| 急性氟乙酰胺中毒患者心肌损伤的临床研究 |
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| 引用本文： | 徐瑞华,杨忠,曹蓉. 急性氟乙酰胺中毒患者心肌损伤的临床研究[J]. 中国医师进修杂志, 2004, 27(19): 19-20 |
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| 作者姓名： | 徐瑞华 杨忠 曹蓉 |
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| 作者单位： | 云南省第一人民医院,急救内科教研室,云南,昆明,650032 |
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| 摘 要： | 目的 观察急性氟乙酰胺中毒患者血清心肌肌钙蛋白T(cTnT)的动态变化。方法 对 92例急性氟乙酰胺中毒者进行血清cTnT、肌酸激酶 (CK)和肌酸激酶同功酶 (CK -MB)检测。结果 发病后 3hcTnT阳性检出率为5 3.8%,明显高于CK(2 0 %)、CK -MB(2 3.1 %) ;中毒后 5dcTnT阳性检出率为 6 9.2 %,而CK和CK -MB仅为 8.0 %和 4 .0 %。结论 (1 )急性氟乙酰胺中毒者存在急性心肌损伤。 (2 )血清cTnT能早期确切诊断急性心肌损伤 ,有较宽的时间诊断窗 ,是心肌损伤早期诊断较敏感和特异的血清标志物。
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| 关 键 词： | 急性中毒 氟乙酰胺 心肌肌钙蛋白T |
| 文章编号： | 1002-0764(2004)10A-0019-02 |
| 修稿时间： | 2004-02-10 |
Clinical study of myocardial injury in patients with acute fluorine acetamide poisoning |
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| XU Rui_hua,YANG Zhong,ZENG Rong. Clinical study of myocardial injury in patients with acute fluorine acetamide poisoning[J]. Chinese Journal of Postgraduates of Medicine, 2004, 27(19): 19-20 |
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| Authors: | XU Rui_hua YANG Zhong ZENG Rong |
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| Abstract: | Objective To observe the changes of serum cTnT in patients with acute fluorine acetamide poisoning and evaluate the clinical significance of cTnT for early diagnosis of acute myocardial injury.Methods At difference time after fluorine acetamide poisoning, serum cTnT, CK and CK-MB of 92 patients were measured. Results The positive rate of cTnT, CK and CK-MB 3 h after fluorine acetamide poisoning were 53.8%, CK 20% and CK-MB 23.5% respectively and 69.2%, 8.0% and 4.0% after 5 days. Conclusion (1) Myocardial injury was presented in patients with acute fluorine acetamide. (2)Serum cTnT is a sensitive and special marker of myocardial injury and diagnosis of acute myocardial injury in earlier stage can be make based on cTnT in patients with acute fluorine acetamide poisoning. |
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| Keywords: | acute poisoning fluorine acetamide cTnT |
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