川崎病冠状动脉损害危险因素的分析

目的探讨川崎病（KD）冠状动脉损害（CAL）的危险因素。方法收集137例KD患儿的临床资料，分析KD冠状动脉损害的危险因素。结果137例川崎病患儿中，冠状动脉损害32例（23．4％）。性别、发病时年龄、发热持续时间、丙种球蛋白使用时间、WBC、CRP及血浆白蛋白水平与冠状动脉扩张的发生密切相关（P〈0．05）；年龄、发热持续时间、CRP与CAL的发生独立相关（P〈0．05）。结论川崎病CAL与惠儿CRP、年龄、发热持续时间密切相关，对小年龄组患儿，如发热时间长、CRP明显升高应给予足够重视。

Analysis of risk factors of coronary artery lesions in Kawasaki disease

Objective To investigate the risk factors of coronary artery lesions （CAL） in Kawasaki disease （KD）. Methods Clinical features of 137 patients with KD were collected. Risk factors associated with coronary artery lesions were analyzed. Results Of the 137 KD patients, there were 32 cases CALs （23.4%）. Univariate analysis demonstrated that gender, age, duration of fever, timing of IVIG therapy, white blood cell count, CRP and serum albumin were related to CAL （P〈0. 05）. Multiple logistic regression analysis indicated CRP, age and duration of fever were independent risk factors for CALs （P〈0. 05）. Conclusion CRP, age, duration of fever had close relationship with CALs. Special attention should be paid on small children with high CRP and long duration of fever.