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甲氨蝶呤治疗异位妊娠的临床分析
引用本文:张虹.甲氨蝶呤治疗异位妊娠的临床分析[J].中国当代医药,2013(15):68-69.
作者姓名:张虹
作者单位:新疆兵团第二师库尔勒医院药械科,新疆库尔勒841000
摘    要:目的 探讨甲氨蝶呤用于治疗异位妊娠的临床效果.方法 对照组给予米非司酮,观察组给予MTX联合米非司酮,观察两组临床疗效及药物不良反应情况.结果 观察组总有效率为86.21%,明显高于对照组的68.97%;肝肾功能异常率为11.49%,明显优于对照组的41.38%,比较差异均具有统计学意义,P均< 0.05,且两组均未出现严重不良反应.结论 甲氨蝶呤治疗异位妊娠临床疗效确切,对保留患者生育功能有积极的临床意义,值得临床应用和推广.

关 键 词:甲氨蝶呤  米非司酮  异位妊娠  临床分析

Clinical analysis of methotrexate for treatment of ectopic pregnancy
Authors:ZHANG Hong
Institution:ZHANG Hong Machinery Department of Xinjiang Regiment of the Two Division in Korla Hospital, Xinjiang Uygur Autonomous Re- gion Xinjiang, Korla 841000, China
Abstract:Objective To explore the clinical effect of MTX for treatment of ectopic pregnancy. Methods The control group was given mifepristone, observation group were given MTX combined with mifepristone, to observe the clinical efficacy and adverse reactions of the two groups of drugs. Results The total effective rate in the observation group was 86.21%, significantly higher than that in control group (68.97%); liver function abnormal rate of 11.49%, significantly better than the control group (41.38%), differences were statistically significant, all P 〈 0.05, and the two groups had no serious adverse reactions. Conclusion Clinical efficacy of the treatment of ectopic pregnancy with methotrexate is effective, has positive clinical significance in patients with retained reproductive function.
Keywords:Methotrexate  Mifepristone  Ectopic pregnancy  Clinical analysis
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