小细胞肺癌与非小细胞肺癌宝石CT能谱研究

目的通过对小细胞肺癌与非小细胞肺癌能谱CT增强扫描，探讨CT能谱成像定量分析在鉴别小细胞肺癌与非小细胞肺癌影的像学价值。方法回顾性选取病理已确诊的小细胞肺癌与非小细胞肺癌各20例，均用宝石能谱CT进行GSI扫描，在宝石能谱成像浏览器（GSIviewer）的软件上进行，得到能谱曲线含碘量图40-140keV能量水平的CT值及斜率值对比，最后进行数据分析。结果增强扫描中40-140keV能量水平的CT值中，40-70keV能量水平的CT值小细胞肺癌组低于非小细胞肺癌组。小细胞肺癌组与非小细胞肺癌组能谱曲线肿瘤内40-70keV兴趣区（ROI）碘含量斜率各为（2．07＋0．76）、（3．08＋1．16），两组组间斜率差异有统计学意义（t=3．23，P〈0．05）。结论小细胞肺癌与非小细胞肺癌能谱成像上碘含量不同的特征，可以初步区分小细胞肺癌与非小细胞肺癌，为影像学鉴别诊断提供一定的参考价值。

Gem energy spectrum CT study for small cell lung cancer and non small cell lung cancer

Objective To explore the application value of quantitative analysis in distinguishing between small cell lung cancer and non-small cell lung cancer by the gem energy spectrum CT. Methods Twenty patients with small cell lung cancer and 20 patients with non-small cell lung cancer confirmed by pathology were collected. All the cases un- derwent GSI imaging of Gem energy spectrum CT, the CT values and slope value on 40-140 keV was got in gemstone spectral imaging viewer （GSI viewer） software. Then data was analyzed and compared. Results In the CT values on 40- 140 keV of gem energy spectrum CT enhancement imaging, the CT values on 40-70 keV in small cell lung cancer group was lower than that in non-small cell lung cancer group. Slope value within the tumor region of interest （ROI） on 40-70 keV was （2.07±0.76） vs （3.08±1.16）, statistical significant difference of slope value was found between the two groups（t = 3.23, P 〈 0.05）. Conclusion The characteristics of iodine content can initially distinguish between small cell lung cancer and non-small cell lung cancer in energy spectrum imaging, and it provide reference value for the differ- ential diagnosis in medical imageology.