结节性硬化综合征的影像诊断价值

目的探讨结节性硬化综合征的影像学表现及其诊断价值。方法回顾27例经临床证实的结节性硬化综合征的cT和MRI资料，分析病变影像学表现。结果CT和MRI显示本组27例（100％）患者存在室管膜下结节，MRI显示26例（90％）患者存在皮层及皮层下结节，表现为脑实质内异常信号灶，T1WI呈低信号，T2WI呈高信号，4例见室管膜下星形细胞瘤，4例合并肾脏血管平滑肌脂肪瘤，1例合并肺部血管淋巴管腺肌瘤病．1例合并肝脏血管平滑肌脂肪瘤。结论结节性硬化综合征有特征性的影像表现，CT显示室管膜下钙化灶敏感．对结节性硬化的诊断有特征性，MRI对非钙化性病灶敏感，能发现更多病变。

Imaging diagnosis value of the tuberous sclerosis syndrome

Objective To discuss the imaging appearances and diagnostic value of tuberous sclerosis syndrome. Methods Reviewed CT and MRI data of 27 patients with tuberous sclerosis syndrome which were proved clinically. Results CT and MRI showed that 27（100%） patients had subependymal nodules, MRI revealed that 26（90%） patients had cortical and subcortical nodules, manifested as cerebral parenchyma abnormal signal range, low signal on T1W1, T2WI showed high signal, 4 cases showed subependymal astrocytoma, 4 cases had renal angiomylipoma, 1 case had pulmonary vascular lymphatic gland disease and 1 case had hepatic angiomylipoma. Conclusion Tuberous sclerosis syndrome has characteristic imaging appearance, CT displays that subependymal calcifications is sensitive, and it is characteristic on the diagnosis of tuberous sclerosis, MRI is sensitive on non-calcified lesions and it can discover more lesions.