阿托伐他汀钙序贯疗法治疗急性心肌梗死介入治疗后上消化道出血的效果观察

目的探讨对急性心肌梗死患者行介入治疗后，采用阿托伐他汀钙序贯疗法预防上消化道出血的疗效。方法共选择急性心肌梗死患者90例，将其依据随机原则分为3组，分别为实验组、观察组以及对照组．各30例。对照组给予安慰剂治疗，实验组给予口服阿托伐他汀钙治疗，观察组则采取阿托伐他汀钙序贯疗法治疗，比较3组治疗效果。结果观察组与实验组的总有效率显著高于对照组（P〈0．05），一级复合终点情况方面比较．观察组与实验组均优于对照组（P〈0．05）。结论应用阿托伐他汀钙序贯疗法治疗预防急性心肌梗死介入治疗后上消化道出血，效果显著，安全性高．值得临床给予大力推广使用。

Effect observation of atorvastatin calcium sequential therapy preventing upper gastrointestinal hemorrhage after interventional therapy on patients with acute myocardium infarction

Objective To observe the efficacy of atorvastatin calcium sequential therapy preventing upper gastrointestinal hemorrhage after interventional therapy on patients with acute myocardium infarction. Methods Ninety patients with acute myocardium infarction were selected and divided into 3 groups randomly, the experiment group, the observation group and the control group, each group for 30 cases. The control group were treated with placebo, the experiment group were treated with oral atorvastatin calcium, and the observation group received atorvastatin calcium sequential therapy. The treatment effect of three groups was compared. Results The total effective rate of the observation group and the experiment group was higher evidently than that of the control group （P 〈 0.05）. As for the first level of composite end point situation, the observation group and the experiment group was better than that of the control group （P 〈 0.05）. Conclusion Applying atorvastatin calcium sequential therapy to treat and prevent upper gastrointestinal hemorrhage after interventional therapy on patients with acute myocardium infarction has evident effect and high safety, which is worthy of wide application in clinical practice.