急诊静脉注射胺碘酮转复阵发性房颤40例疗效分析

目的探讨急诊静脉注射胺碘酮转复阵发性心房颤动（房颤）的临床疗效。方法选择本院2009～2012年急诊收治80例阵发性房颤患者的资料，根据其转复方法分为观察组及对照组，各40例，观察组采用静脉注射胺碘酮治疗，对照组采用静脉注射普罗帕酮治疗，对两组患者的转复效果及安全性进行评价。结果观察组患者在用药后12h内转复率高于对照组，比较差异有统计学意义（P〈0．05）；两组患者在药物不良反应方面比较，差异无统计学意义（P〉0．05）。结论静脉注射胺碘酮转复阵发性房颤转复时间短，药物不良反应发生率低，值得在急诊科推广。

Efficacy analysis of emergency intravenous amiodarone in treatment of paroxysmal atrial fibrillation in 40 cases

Objective To discuss the clinical efficacy of emergency intravenous amiodarone treatment to paroxysmal atrial fibrillation （PAF）. Methods Eighty PAF patients treated in our emergency department from 2009 to 2012 were di- vided into observation group and control group according to their cardioversion treatment with 40 patients respectively. Patients in the observation group were given intravenous amiodarone while patients in the control group were given intravenous propafenone. Cardioversion effects and safety were measured and compared between the two groups. Results Statistically significant difference （P 〈 0.05） exited in cardioversion rate within 12 hours after treatment between the two groups in which observation group took less time to have cardioversion. No statistically significant difference （P 〉 0.05） exited in adverse effects between the two groups. Conclusion Intravenous amiodarone treatment is worthy of application in emergency department to treat PAF with short time to cause cardioversion and low rate of adverse effects.