| 脑梗死患者活化血小板的检测及其临床意义 |
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| 引用本文： | 吴海琴,吴月飞,吴晓琳,王虎清,杨慧云. 脑梗死患者活化血小板的检测及其临床意义[J]. 中国血液流变学杂志, 2008, 18(4) |
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| 作者姓名： | 吴海琴 吴月飞 吴晓琳 王虎清 杨慧云 |
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| 作者单位： | 1. 西安交通大学医学院第二附属医院,神经内科,陕西西安,710004
2. 西安交通大学医学院第二附属医院,血液科,陕西,西安,710004 |
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| 摘 要： | 目的 观察脑梗死患者血小板膜糖蛋白CD62p表达,探讨脑梗死患者血小板活化的临床意义.方法 用流式细胞术检测脑梗死组57例和对照组30例全血血小板膜糖蛋白CD62p的阳性率和平均荧光强度,同时对脑梗死患者进行神经功能缺失评分.结果 脑梗死组血小板CD62p的阳性率及平均荧光强度均显著高于对照组(P＜0.01),且与病情严重程度明显相关.结论 脑梗死时血小板处于高度活化状态,监测血小板活化程度对预测病情轻重及指导临床用药均有重要意义.
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| 关 键 词： | 血小板活化 脑梗死 流式细胞术 |
Detection of Activated Platelet and Its Clinical Significance in Cerebral Infarction |
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| WU Hai-qin,WU Yue-fei,WU Xiao-lin,WANG Hu-qing,YANG Hui-yun. Detection of Activated Platelet and Its Clinical Significance in Cerebral Infarction[J]. Chinese Journal of Hemorheology, 2008, 18(4) |
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| Authors: | WU Hai-qin WU Yue-fei WU Xiao-lin WANG Hu-qing YANG Hui-yun |
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| Abstract: | Objective To investigate the expression of platelet membrane glycoprotein in patients with cerebral infarction and study clinical significance of platelet activation of cerebral infarction.Methods Flow cytometry was employed to detect CD62p expression on circulating platelet in 57 patients with cerebral infarction and 30 controls,and CSS was measured in patients with cerebral infarction.Results The positive percentage and the fluorescence intensity of CD62p on platelets were significantly increased in patie... |
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| Keywords: | CD62p |
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