| 冷冻对大鼠脂质过氧化反应影响的研究 |
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| 引用本文： | 唐瞻贵,孙科柱.冷冻对大鼠脂质过氧化反应影响的研究[J].口腔医学,1998,18(1):7-8. |
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| 作者姓名： | 唐瞻贵 孙科柱 |
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| 作者单位： | 湖南医科大学湘雅医院口腔颌面外科，湖南医科大学免疫室 |
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| 摘 要： | 作者采用荧光法，动态观察了冷冻前后１０个不同时期大鼠血清丙二醛（Ｍａｌｏｎｄｉａｌｄｅｈｙｄｅ，简称ＭＤＡ）浓度变化．研究结果表明，脂质过氧化反应参与了冷冻损伤及损伤后修复的全过程，ＭＤＡ的变化规律与冷冻后的临床过程相吻合
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| 关 键 词： | 冷冻外科 丙二醇 氧自由基 |
The Effects of Cryosurgery on Lipid Peroxidation in Rats |
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| Tang Zhangei,Sheng Zihua,Liu Sufan,Xie Xiaoli.The Effects of Cryosurgery on Lipid Peroxidation in Rats[J].Stomatology,1998,18(1):7-8. |
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| Authors: | Tang Zhangei Sheng Zihua Liu Sufan Xie Xiaoli |
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| Abstract: | The aim of this study was to explore the relationship between cryosurgery and oxygen free radicals.60 Wistar rats were divided randomly into 10 groups.Rats of 9 groups were treated with cryosurgery to the angle mucosa of mouth for 30 seconds,the rest group was taken as control.Blood of the animals in different periods were taken for determining the concentration of serum malondialdehyde (MDA) with fluorimetry.The results show that the higher levels of serum MDA are found after cryosurgery.The two peak values are at 4th and 7th week.The lipid peroxidation have taken part in the all cryosurgery process including cryothreapy and restoration.The all changes of serunm MDA are keeping with the clinic process. |
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| Keywords: | Cryosurgery Malondialdehyde Oxygen free radicals |
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