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| 比浊法测定阿奇霉素效价的研究 | |
| 引用本文： | 王康俊,李伟,孙旭亥.比浊法测定阿奇霉素效价的研究[J].中国药房,2007,18(31):2459-2461. |
| 作者姓名： | 王康俊 李伟 孙旭亥 |
| 作者单位： | 1. 海南省药品检验所,海口市,570216 2. 海南九芝堂药业有限公司,海口市,570311 3. 河北恒利集团制药股份有限公司,沙河市,054109 |
| 摘 要： | 目的:建立测定阿奇霉素效价的方法。方法:采用比浊法测定阿奇霉素的效价,并与管碟法比较。结果:阿奇霉素检测浓度的线性范围为0.4～2.0I U.mL-1(r=0.999 1) ;回收率为99.70%～100.02%(RSD为0.22%～0.46%) ;比浊法与管碟法的测定结果无显著性差异。结论:本方法操作更快捷、方便。 |
| 关 键 词： | 比浊法 阿奇霉素 效价测定 比较 |
| 文章编号： | 1001-0408（2007）31-2459-03 |
| 收稿时间： | 2007-09-03 |
| 修稿时间： | 2007-10-11 |
Determination of the Titer of Azithromycin by Turbidimetric Method |
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| WANG Kangjun,LI Wei,SUN Xuhai.Determination of the Titer of Azithromycin by Turbidimetric Method[J].China Pharmacy,2007,18(31):2459-2461. | |
| Authors: | WANG Kangjun LI Wei SUN Xuhai |
| Abstract: | OBJECTIVE: To develop a method for the determination of the titer of azithromycin. METHODS: Turbidimetric method was adopted to determine azithromycin and which was compared with cup-plate method. RESULTS: The linear range of azithromycin was 0.4～2.0IU·mL-1(r=0.999 1), with its recovery rate at 99.70%～100.02%(RSD=0.22%～0.46%), the determination results of 2 kinds of methods was no significant difference. CONCLUSION: Turbidimetric method was proved to be more rapid and convenient than the cup-plate method. |
| Keywords: | Turbidimetry Azithromycin Titer determination Comparison |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |