奥扎格雷治疗急性脑梗死81例临床研究

目的: 观察奥扎格雷治疗急性缺血性脑梗死的临床疗效。方法: 将162例诊断明确的急性脑梗死患者随机分成治疗组和对照组各81例。对照组采用急性脑梗死的常规治疗措施,治疗组在对照组的基础上加用奥扎格雷80 mg静脉滴注,每天1次。分别于治疗前和治疗后14天进行神经功能缺损和临床疗效的评定。结果: 经14天的治疗后,治疗组的神经功能缺损评分低于对照组,差异有统计学意义(P < 0.01);治疗组总有效率88.89%,对照组总有效率76.54%,2组差异有统计学意义(P< 0.01)。结论: 奥扎格雷治疗急性缺血性脑梗死的临床疗效和安全性肯定,值得临床推广使用。

Clinical study of the effects of ozagrel on 81 acute ischemic stroke patients

Objective：To observe the clinical effects and safety of ozagrel in treatment of acute ischemic stroke.Methods：One hundred and sixty-two patients with acute ischemic stroke were randomly divided into control group and treatment group,each 81 patients.The patients in control group were treated with common western medicine,while in treatment group was given ozagrel except the common western medicine.Before and after 14 days′ treatment,the neurologic impairment and clinical curative effect in the two groups were evaluated.Results：The therapeutic effect rate in the treatment group was 88.89%,and that in control group was 76.54%,there was significantly statistical difference in the two groups（P0.01）.Conclusions：Ozagrel is effective and safe in treatment of acute ischemic stroke and worthy of being widely used in clinic.