| 下肢动脉硬化闭塞症药物治疗过程中CD62P、CD63的改变及其意义 |
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| 引用本文： | 许克,余昌俊,余康敏,余鑫. 下肢动脉硬化闭塞症药物治疗过程中CD62P、CD63的改变及其意义[J]. 安徽医科大学学报, 2011, 46(7): 693-695 |
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| 作者姓名： | 许克 余昌俊 余康敏 余鑫 |
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| 作者单位： | 安徽医科大学第一附属医院血管外科,合肥,230022;安徽医科大学第一附属医院血管外科,合肥,230022;安徽医科大学第一附属医院血管外科,合肥,230022;安徽医科大学第一附属医院血管外科,合肥,230022 |
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| 摘 要： | 目的 探讨下肢动脉硬化闭塞症(ASO)患者CD62p、CD63表达率及其在抗血小板药物治疗中的变化.方法 以流式细胞术检测血小板膜标志物CD62p、CD63的表达率评价血小板活化.选取ASO患者和志愿者各20例,实验组给予阿司匹林肠溶片0.1 g、盐酸氯吡格雷片75 mg每天一次,口服2周,分别于第1、3、7、14天检...
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| 关 键 词： | 动脉硬化 闭塞性/药物疗法 下肢 流式细胞术 血小板活化 |
The change and significance of CD62p,CD63 in arteriosclerosis obliterans patients during drug therapy |
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| Xu Ke,Yu Changjun,Yu Kangmin,et al. The change and significance of CD62p,CD63 in arteriosclerosis obliterans patients during drug therapy[J]. Acta Universitis Medicinalis Anhui, 2011, 46(7): 693-695 |
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| Authors: | Xu Ke Yu Changjun Yu Kangmin et al |
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| Affiliation: | Xu Ke,Yu Changjun,Yu Kangmin,et al(Dept of Vascular Surgery,The First Affiliated Hospital of Anhui Medical University,Hefei 230022) |
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| Abstract: | Objective To study the expression rate of platelet activation markers CD62p,CD63 in arteriosclerosis obliterans(ASO)patients and the chang during antiplatelet therapy.Methods The expression rate of platelet membrane markers CD62p,CD63 were detected by flow cytometry,then evaluated the degree of platelet activation.Selected 20 healthy people as the normal group,while 20 ASO patients as the experimental group who were given aspirin enterosoluble tablets 0.1 g and clopidogrel hydrochloride tablets 75 mg each d... |
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| Keywords: | arteriosclerosis obliterans/durg therapy lower limbs flow cytometry platelet activation |
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