复方丙酸氯倍他索软膏联合超脉冲CO_2点阵激光治疗慢性湿疹的临床研究

目的探讨复方丙酸氯倍他索软膏联合超脉冲CO_2点阵激光治疗慢性湿疹的临床疗效。方法收集我科治疗的113例慢性湿疹患者,随机分成2组,试验组57例,采用超脉冲CO_2点阵激光联合复方丙酸氯倍他索乳膏治疗;对照组56例,外用复方丙酸氯倍他索乳膏治疗。治疗4周后观察两组临床疗效及不良反应。结果治疗4周后,试验组有效率高于对照组(94.74%vs.80.36%),两组比较差异有统计学意义(χ~2=5.38,P=0.02);治疗后6个月,试验组复发率低于对照组(14.03%vs.23.14%),两组比较差异有统计学意义(χ~2=5.23,P=0.02),两组不良反应发生率比较(8.77%vs.7.14%)差异无统计学意义(χ~2=0.10,P=0.75)。结论复方丙酸氯倍他索乳膏联合超脉冲CO_2点阵激光治疗慢性湿疹效果良好,操作方便,患者耐受性良好,适于临床应用推广。

Clinical study on the effect of ultrapulsed fractional CO_2 laser combined with compound clobetasol propionate ointment in the treatment of chronic eczema