| 灵芝提取物镇痛抗炎作用研究 |
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| 引用本文： | 陈伟,陈美华,刘晓鹏,武晓娟,高允生,朱玉云. 灵芝提取物镇痛抗炎作用研究[J]. 泰山医学院学报, 2006, 27(2): 102-103 |
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| 作者姓名： | 陈伟 陈美华 刘晓鹏 武晓娟 高允生 朱玉云 |
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| 作者单位： | 1. 泰山医学院药学院,山东,泰安,271000
2. 中国人民解放军第八十八医院,山东,泰安,271000 |
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| 摘 要： | 目的研究灵芝提取物的镇痛与抗炎作用。方法用冰醋酸化学刺激疼痛模型和二甲苯诱导的鼠耳肿胀炎症模型，观察灵芝提取物的镇痛作用与抗炎作用。结果灵芝提取物能明显减少冰醋酸诱导的小鼠扭体次数（P〈0．01），对二甲苯诱导的鼠耳肿胀有明显的抑制作用（P〈0．01）。结论灵芝提取物具有镇痛和抗炎作用。
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| 关 键 词： | 灵芝 镇痛 抗炎 小鼠 |
| 文章编号： | 1004-7115（2006）02-0102-02 |
| 收稿时间： | 2005-11-06 |
| 修稿时间： | 2005-11-26 |
Analgesic and anti-inflammatory effects of Ganoderma lucidum extractive |
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| CHEN Wei,CHEN Mei-hua,LIU Xiao-peng,WU Xiao-juan,GAO Yun-sheng,ZHU Yu-yun. Analgesic and anti-inflammatory effects of Ganoderma lucidum extractive[J]. Journal of Taishan Medical College, 2006, 27(2): 102-103 |
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| Authors: | CHEN Wei CHEN Mei-hua LIU Xiao-peng WU Xiao-juan GAO Yun-sheng ZHU Yu-yun |
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| Affiliation: | 1. Pharmaceutical Institute of Taishan Medical College, Taian, 271000,China; 2. Grade 2003, Pharmaceutical Undergraduate of Taishan Medical College, Taian, 271000,China; 3. The 88th Hospital of PLA ,Taian ,271000,China |
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| Abstract: | Objective:To explore the anti-inflammatory and analgesic effects of Ganoderma lucidum extractive.Methods:Analgesic and anti-inflammatory effects were detected by analgesic model of mice twist and inflammatory model of dimethyl-benzene-induced ear swelling in mice.Results:Ganoderma lucidum extractive decreased the rolling reaction times of mice,and restrained the swelling of mice ears at the doses of 0.015g/kg and 0.030g/kg(P<0.01).Conclusion:Ganoderma lucidum extractive has analgesic and anti-inflammatory effects. |
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| Keywords: | Ganoderma lucidum analgesic anti-inflammatory mice |
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