前瞻性研究微生态制剂用于小儿腹泻的疗效观察

目的为了进一步提高小儿腹泻的临床治疗效果,探讨和分析临床应用微生态制剂的可行性和安全性。方法将2012年2月—2013年2月来我院儿科就诊的160例小儿腹泻患者按照随机双盲的原则分为治疗组和观察组,其中观察组患者治疗上给予常规止泻、抗感染及对症支持治疗,治疗组患者在常规抗感染、止泻及对症支持治疗的同时给予微生态制剂,对比和分析两组患者的临床治疗效果。结果经过对比研究发生,治疗组患者的临床治疗总有效率（92.5%）显著优于观察组患者（65.0%）,且两组患者比较差异具有统计学意义（P〈0.05）。结论对于小儿腹泻患者在常规抗感染和对症支持治疗的同时给予微生态制剂,可以显著提高临床治疗效果,值得推广。

Observation on effect of prospective study of probiotics on infantile diarrhea

Objective To further improve the clinical effect of infantile diarrhea,explore and analyze the feasibility and security of clinical application of probiotics.Methods Divided 160 cases of infantile diarrhea patients treated in our hospital during February 2012 to February 2013 in accordance with the principle of randomized double-blind into treatment group and observation group,the observation group was given the conventional anti-diarrhea,anti-infective and symptomatic and supportive treatment,the treatment group was treated by probiotics on the basis of observation group,compared and analyzed the clinical effect of the two groups.Results Through contrasting research,the clinical total effective rate of treatment group（92.5%） was significantly higher than observation group were（65.0%）,the differences between the two groups were statistically significant（P0.05）.Conclusion Treating the infantile diarrhea patients by probiotics while the patients are in the conventional anti-infective and symptomatic and supportive treatment can significantly improve clinical effects,it deserves to be promoted.