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重组组织型纤溶酶原激活剂静脉溶栓治疗急性缺血性脑卒中前后循环梗死疗效比较
引用本文:谭倩,许康,周瑞,晏小琼,余勇飞. 重组组织型纤溶酶原激活剂静脉溶栓治疗急性缺血性脑卒中前后循环梗死疗效比较[J]. 疑难病杂志, 2011, 10(11): 822-823. DOI: 10.3969/j.issn.1671-6450.2011.11.008
作者姓名:谭倩  许康  周瑞  晏小琼  余勇飞
作者单位:湖北省新华医院神经内科,武汉,430071
摘    要:目的比较使用重组组织型纤溶酶原激活剂(rt-PA)静脉溶栓治疗急性缺血性卒中患者前后循环梗死的临床疗效。方法回顾性分析3l例发病在6h内的急性缺血性脑卒中患者的临床表现、治疗方法及疗效。其中前循环梗死22例,后循环梗死9例,在溶栓前和溶栓后2h、24h、7d时,定期对患者进行神经功能缺损测评(NIHSS评分),并进行比较。结果静脉溶栓治疗前前循环与后循环组间患者血压、NIHSS评分、发病时间、住院天数等基础情况比较差异无统计学意义(P>0.05)。静脉溶栓治疗后各时间点2组均较溶栓前显著下降(P<0.05),且后循环NIHSS评分下降较前循环明显(P<0.05)。结论 rt-PA静脉溶栓治疗急性缺血性卒中后循环梗死临床疗效较前循环更明显。

关 键 词:脑卒中,缺血性,急性  重组组织型纤溶酶原激活剂  静脉溶栓

Comparison the therapeutic effective between anterior circulation and posterior circulation with recombinant tissue plasminogen activator thrombolysis on acute ischemic stroke
TAN Qian,XU Kang,ZHOU Rui,et al.. Comparison the therapeutic effective between anterior circulation and posterior circulation with recombinant tissue plasminogen activator thrombolysis on acute ischemic stroke[J]. Journal of Difficult and Complicated Cases, 2011, 10(11): 822-823. DOI: 10.3969/j.issn.1671-6450.2011.11.008
Authors:TAN Qian  XU Kang  ZHOU Rui  et al.
Affiliation:TAN Qian,XU Kang,ZHOU Rui,et al.Xinhua Hospital of Hubei Province,Wuhan 430071,China
Abstract:Objective To explore the clinical effects of infarction in the use of recombinant tissue plasminogen activator (rt-PA) thrombolytic therapy for acute ischemic stroke between anterior circulation and posterior circulation.Methods Retrospective analysis of 31 patients within 6h of onset in acute ischemic stroke patients with clinical manifestations,treatment and efficacy,of which 22 cases of anterior circulation infarction,9 cases of posterior circulation infarction.The neurological deficits(NIHSS score) were...
Keywords:Stroke  ischemic  acute  Recombinant tissue plasminogen activator  Intravenous thrombolytic therapy  
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