Usefulness of diffusion-weighted imaging for differentiating between desmoid tumors and malignant soft tissue tumors |
| |
Authors: | Oka Kiyoshi Yakushiji Toshitake Sato Hiro Fujimoto Toru Hirai Toshinori Yamashita Yasuyuki Mizuta Hiroshi |
| |
Affiliation: | Department of Orthopaedic and Neuromusculoskeletal Surgery, Faculty of Medical and Pharmaceutical Sciences, Kumamoto University, Kumamoto, Japan. okaokay5888@yahoo.co.jp |
| |
Abstract: | Purpose To evaluate the usefulness of diffusion‐weighted imaging (DWI) for differentiating between desmoid tumors and malignant soft tissue tumors. Materials and Methods Conventional MRI and DWI were performed for 8 desmoid tumors and 74 malignant soft tissue tumors. DWI was obtained with a single‐shot echo‐planar imaging sequence using a 1.5 Tesla (T) MR imager. DW images were acquired with motion‐probing gradient pulses applied along three directions (x, y, and z axes) with three b‐factors (0, 500, and 1000 s/mm2). Two observers blinded to clinical information measured three regions of interest within the solid tumor and selected a minimum apparent diffusion coefficient () in each lesion. The mean ADC of desmoid tumors was calculated and compared with that of malignant soft tissue tumors using the Mann‐Whitney U test. Results The mean ADC of desmoid tumors and malignant soft tissue tumors was 1.36 ± 0.48 × 10−3 mm2/s and 0.88 ± 0.20 × 10−3 mm2/s (mean ± SD), respectively. The mean ADC of the desmoid tumors was significantly higher than that of malignant soft tissue tumors (P < 0.01). Conclusion DWI is considered to be useful for differentiating between desmoid tumors and malignant soft tissue tumors. In the future, further investigation in a large series is necessary. J. Magn. Reson. Imaging 2011;33:189–193. © 2010 Wiley‐Liss, Inc. |
| |
Keywords: | desmoids tumors malignant soft tissue tumor diffusion‐weighted imaging (DWI) apparent diffusion coefficient (ADC) |
本文献已被 PubMed 等数据库收录! |
|