| 缺血性脑血管病白细胞粘附功能和变形能力的变化 |
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| 引用本文： | 谭润鸾,刘成玉,万秀霞,纪新强,杨茂鹏.缺血性脑血管病白细胞粘附功能和变形能力的变化[J].青岛大学医学院学报,1995(1). |
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| 作者姓名： | 谭润鸾 刘成玉 万秀霞 纪新强 杨茂鹏 |
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| 作者单位： | 青岛市市北区医院 |
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| 摘 要： | 采用ＷＪＹ－Ⅲ型体外血栓血小板粘附两用仪和ＤＸＣ－３００型核孔膜红细胞变形能力测定仪，检测了８３例缺血性脑血管病（ＩＣＶＤ）病人白细胞粘附功能（ＬＡＦ）和白细胞变形能力（ＬＤ）的变化，以探讨其在ＩＣＶＤ发生和发展中的作用。结果显示，ＩＣＶＤ病人白细胞粘附率（ＬＡＲ）和白细胞滤过指数（Ｆ）均明显增高，与对照组相比，差异有极显著性（Ｐ＜０．００１）。且随着病情加重、梗塞面积的扩大及预后不良，ＬＡＲ和ＩＦ的增高逐渐明显。提示ＬＡＦ增高和ＬＤ降低与ＩＣＶＤ发生有一定关系。
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| 关 键 词： | 脑血管意外，脑缺血，白细胞，流变学，粘着性 |
STUDY OF LEUKOCYTE ADHESION FUNCTION AND LEUKOCYTE DEFORMABILITY IN PATIENTS WITH ISCHEMIC CEREBROVASCULAR DISEASE |
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| Tan Runluan,Liu Chengyu,WanXiuxia,et al.STUDY OF LEUKOCYTE ADHESION FUNCTION AND LEUKOCYTE DEFORMABILITY IN PATIENTS WITH ISCHEMIC CEREBROVASCULAR DISEASE[J].Acta Academiae Medicinae Qingdao Universitatis,1995(1). |
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| Authors: | Tan Runluan Liu Chengyu WanXiuxia |
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| Institution: | Department of Diagnostics |
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| Abstract: | The changes in the leukocyte adhesion function(LAF) and leukocyte deformability(LD) were measured in 83 patients with ischemic cerebrovascular disease(ICVD),in order to study their role in the occurrence and development of ICVD.The results showed that the leukocyte adhesion rate(LAR) and the leukocyte filtration index (IF) were significantly higher in the patients than in the controls(P<0.001),and their increase became more obvious as the patient's condition aggravated,the infarction extended and the prognosis worsened,These results indicate that the LAF and LD may contribute to the occurrence and development of ICVD. |
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| Keywords: | cerebrovascular disorders cerebral ischemia leukocyte adhesivenesss |
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