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乌桕叶化学成分研究
引用本文:王洪庆,赵春阳,陈若芸. 乌桕叶化学成分研究[J]. 中国中药杂志, 2007, 32(12): 1179-1181
作者姓名:王洪庆  赵春阳  陈若芸
作者单位:中国医学科学院,中国协和医科大学,药物研究所,中草药物质基础与资源利用教育部重点实验室,北京,100050
摘    要:目的:研究乌桕Sapium sebiferum叶中的化学成分。方法:利用硅胶柱色谱及制备型HPLC进行分离纯化,根据各种光谱技术进行化合物鉴定。结果:分离得到9个化合物,分别为莽草酸(1),山柰酚(2),槲皮素(3),异槲皮苷(4),金丝桃苷(5),山柰酚-3-O-β-D-葡萄糖苷(6),山柰酚-3-O-β-D-半乳糖苷(7),没食子酸(8),芦丁(9)。结论:化合物1,5,6,7为首次从该属植物中分离得到,化合物9为首次从该种植物中分到。

关 键 词:乌桕  大戟科  化学成分
文章编号:1001-5302(2007)12-1179-03
收稿时间:2006-12-20
修稿时间:2006-12-20

Studies on chemical constituents from leaves of Sapium sebiferum
WANG Hong-qing; ZHAO Chun-yang; CHEN Ruo-yun. Studies on chemical constituents from leaves of Sapium sebiferum[J]. China Journal of Chinese Materia Medica, 2007, 32(12): 1179-1181
Authors:WANG Hong-qing   ZHAO Chun-yang   CHEN Ruo-yun
Affiliation:Institute of Materia Medica, Chenese Academy of Medical Sciences and Peking Union Medical College; Key Laboratory of Bioactive Substances and Resources Utilization of Chinese Herbal Medicine, Ministry of Education, Beifing 100050, China
Abstract:OBJECTIVE: To study the chemical constituents from leaves of Sapium sebiferum. METHOD: The compounds were isolated and purified by silic gel column chromatography and preparative HPLC. The structures were identified by various spectral evidence. RESULT: Nine compounds were obtained and they were shikimic acid (1), kaempferol (2), quercetin (3), isoquercein (4), hyperin (5), kaempferol-3-O-beta-D-glucopyranoside (6), kaempferol-3-O-beta-D-glueopyranoside (7), gallic acid (8), rutin (9). CONCLUSION: Compounds 1, 5, 6 and 7 are isolated from this genus for the first time and compound 9 is isolated from this plant for the first time.
Keywords:Sapium sebiferum   Euphorbiaceae   chemical constituents
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