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间充质干细胞在肝脏的归巢及分化机制
引用本文:林沪,陈黎明,叶文华,施明,王福生. 间充质干细胞在肝脏的归巢及分化机制[J]. 胃肠病学和肝病学杂志, 2010, 19(3)
作者姓名:林沪  陈黎明  叶文华  施明  王福生
作者单位:1. 解放军军医进修学院
2. 解放军第302医院感染6科,北京,100039
基金项目:国家杰出青年科学基金 
摘    要:间充质干细胞可通过旁分泌营养机制和分化为肝实质细胞等修复肝组织,移植间充质干细胞将成为临床治疗肝病的一种重要方法。本文介绍了间充质干细胞在肝损伤条件下,归巢到损伤肝脏并分化为肝实质细胞的可能机制。

关 键 词:间充质干细胞  归巢  分化

Mechanism of homing and differentiation of mesenchymal stem cells in liver
LIN Hu,CHEN Liming,YE Wenhua,SHI Ming,WANG Fusheng. Mechanism of homing and differentiation of mesenchymal stem cells in liver[J]. Chinese Journal of Gastroenterology and Hepatology, 2010, 19(3)
Authors:LIN Hu  CHEN Liming  YE Wenhua  SHI Ming  WANG Fusheng
Affiliation:LIN Hu,CHEN Liming,YE Wenhua,SHI Ming,WANG FushengSixth Department of Infectious Diseases,the 302 Hospital of PLA,Beijing 100039,China
Abstract:Mesenchymal stem cells can restore the hepatic function by paracrine mechanism and differentiation into hepatic parenchymal cells,so transplantation of mesenchymal stem cells would be the important therapic method for liver disease.This review introduced the mechanism of homing and differentiation of mesenchymal stem cells in liver.
Keywords:Mesenchymal stem cells  Homing  Differentiation  
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