| FOLLOW-UP STUDY ON AUDITORY EVOKED POTENTIAL P50 IN FIRST-EPISODE SCHIZOPHRENIA |
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| 引用本文： | 陈兴时,张明岛,王红星,楼翡璎,梁建华,陈冲. FOLLOW-UP STUDY ON AUDITORY EVOKED POTENTIAL P50 IN FIRST-EPISODE SCHIZOPHRENIA[J]. 上海第二医科大学学报, 2006, 18(1): 7-9,14 |
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| 作者姓名： | 陈兴时 张明岛 王红星 楼翡璎 梁建华 陈冲 |
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| 作者单位： | Shanghai Institute of Mental HealthShanghai 200030 China，Shanghai Institute of Mental HealthShanghai 200030，China，Shanghai Institute of Mental HealthShanghai 200030，China，Shanghai Institute of Mental HealthShanghai 200030，China，Shanghai Institute of Mental HealthShanghai 200030，China，Shanghai Institute of Mental HealthShanghai 200030，China |
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| 摘 要： | Objective To investigate the variation of auditory evoked potential P50 in first-episode schizo- phrenia. Methods P50 was recorded from 66 schizophrenics and 92 normal controls with American Brova instrument, and assessing their psychotic symptoms with PANSS. Results Compared with NC, schizophrenics showed sensory gating deficit, reflecting by increased S2/S1 ratio (NC: 42±21% , Sch:81±40% ,P <0. 01). No significant correlation was found between PANSS score and the three markers for assessing the sensory gating, such as the S2/S1 ratio, S2-S1, and 100 (1 -S2/S1) (P > 0. 05). Schizophrenics showed no differences with P50 markers between the 5 weeks and 12 weeks of treatment. Conclusion P50 might be biological trait marker of schizophrenia.
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| 关 键 词： | 听觉诱发电位P50 精神分裂症 病理机制 治疗 |
| 收稿时间： | 2005-09-05 |
FOLLOW-UP STUDY ON AUDITORY EVOKED POTENTIAL P50 IN FIRST-EPISODE SCHIZOPHRENIA |
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| CHEN Xing-shi,ZHANG Ming-dao,WANG Hong-xing,LOU Fei-yui,LIANG Jian-hua,CHEN Chong. FOLLOW-UP STUDY ON AUDITORY EVOKED POTENTIAL P50 IN FIRST-EPISODE SCHIZOPHRENIA[J]. Journal of Shanghai Second Medical University(Foreign Language Edition), 2006, 18(1): 7-9,14 |
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| Authors: | CHEN Xing-shi ZHANG Ming-dao WANG Hong-xing LOU Fei-yui LIANG Jian-hua CHEN Chong |
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| Abstract: | |
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| Keywords: | schizophrenia sensory gating P50 trait marker |
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