益肾泻浊方血清对慢胜肾衰大鼠肾小球系膜细胞的影响 |
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引用本文: | 徐成钢,吴志英.益肾泻浊方血清对慢胜肾衰大鼠肾小球系膜细胞的影响[J].中国中西医结合杂志,1997,17(7):423-424. |
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作者姓名: | 徐成钢 吴志英 |
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摘 要: | 目的:观察益肾泻浊方对大鼠肾小球系膜细胞增殖的影响。方法:采用灌胃法给予健康大鼠及实验性肾功能衰竭大鼠益肾泻浊方冲剂,观察给药后大鼠血清对肾小球系膜细胞增殖的影响。结果:与灌服生理盐水的对照大鼠相比较,前者能明显抑制系统细胞的增殖。结论:该方能延缓慢性肾功能衰竭进程。
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关 键 词: | 益肾泻浊方 肾功能衰竭 中医药疗法 |
Effect of Yishen Xiezhou Recipe on Mesangium Cell of Chronic Renal Failure Rats |
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Authors: | C G Xu Z Y Wu |
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Institution: | Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine. |
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Abstract: | OBJECTIVE: To observe the effect of Yishen Xiezhuo Recipe (YSXZR) on glomerular mesangium cell (MSC) proliferation. METHODS: YSXZR was given to healthy and experimental CRF rats by gastrogavage, and the effect of their serum on MSC proliferation was observed. RESULTS: The serum could obviously inhibit the MSC proliferation. Compared with control rats to which physiological saline was given, the difference was significant (P < 0.01). CONCLUSION: YSXZR could postpone CRF progress. |
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Keywords: | Yishen Xiezhuo Recipe glomerular mesangium cell proliferation |
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