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益肾泻浊方血清对慢胜肾衰大鼠肾小球系膜细胞的影响
引用本文:徐成钢,吴志英.益肾泻浊方血清对慢胜肾衰大鼠肾小球系膜细胞的影响[J].中国中西医结合杂志,1997,17(7):423-424.
作者姓名:徐成钢  吴志英
摘    要:目的:观察益肾泻浊方对大鼠肾小球系膜细胞增殖的影响。方法:采用灌胃法给予健康大鼠及实验性肾功能衰竭大鼠益肾泻浊方冲剂,观察给药后大鼠血清对肾小球系膜细胞增殖的影响。结果:与灌服生理盐水的对照大鼠相比较,前者能明显抑制系统细胞的增殖。结论:该方能延缓慢性肾功能衰竭进程。

关 键 词:益肾泻浊方  肾功能衰竭  中医药疗法

Effect of Yishen Xiezhou Recipe on Mesangium Cell of Chronic Renal Failure Rats
Authors:C G Xu  Z Y Wu
Institution:Yueyang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine.
Abstract:OBJECTIVE: To observe the effect of Yishen Xiezhuo Recipe (YSXZR) on glomerular mesangium cell (MSC) proliferation. METHODS: YSXZR was given to healthy and experimental CRF rats by gastrogavage, and the effect of their serum on MSC proliferation was observed. RESULTS: The serum could obviously inhibit the MSC proliferation. Compared with control rats to which physiological saline was given, the difference was significant (P < 0.01). CONCLUSION: YSXZR could postpone CRF progress.
Keywords:Yishen Xiezhuo Recipe  glomerular mesangium cell proliferation
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