骨松Ⅱ号治疗绝经后骨质疏松症临床生化指标观察 |
| |
引用本文: | 史炜镔,张昊,杜宁,王济纬,符诗聪,杨建,曲克服,李国衡.骨松Ⅱ号治疗绝经后骨质疏松症临床生化指标观察[J].中国中西医结合杂志,1997,17(7):398-400. |
| |
作者姓名: | 史炜镔 张昊 杜宁 王济纬 符诗聪 杨建 曲克服 李国衡 |
| |
作者单位: | 上海第二医科大学 |
| |
摘 要: | 目的:评估骨松Ⅱ号治疗绝经后骨质疏松症的疗效,并试图揭示其机理。方法:以35例年龄49-62岁,绝经时间5.6年的绝经后骨质疏松妇女为治疗对象,于治疗后6-9个月、1-2年分期随访。疗程6个月-2年1个月不等,平均疗程为1年2个月。治疗前后作血雌二醇(E2)、睾酮(T)、晨尿Ca/Cr、24h尿Ca/Cr、24h尿E2、24h尿羟脯氨酸(HOP)等生化指标的测定。结果:治疗6-9个月及治疗1-2年
|
关 键 词: | 骨松Ⅱ号 绝经后 骨质疏松症 中医药疗法 |
Clinical biochemical observations on treatment for postmenopausal osteoporosis with gusong-II] |
| |
Authors: | W B Shi H Zhang N Du |
| |
Institution: | Ruijin Hospital, Shanghai Second Medical University. |
| |
Abstract: | OBJECTIVE: To evaluate the curative effect of Cusong II for postmenopausal osteoporosis, and try to reveal its mechanism. METHODS: Thirty-five women, 49 to 62 years old, with 5.6 years menopause were treated as the subjects and followed for 6-9 months, 1-2 years. The course of treatment ranged from 6 months to 2 years and 1 month, and the average treatment period was 1 year and 2 months. Some related biochemical markers, such as serum estradiol (E2), testosterone (T), lasting morning urinary Ca/Cr, 24 h urinary Ca/Cr, 24 h urinary E2, 24 h urinary hydroxyproline (HOP), were measured before and after treatment. RESULTS: After 6-9 months or 1-2 years, the levels of serum E2 and 24 h urinary E2 were raised significantly, while the levels of serum T and urinary Ca/Cr reduced evidently after 1- or 2- year treatment. The levels of serum E2 and 24 h urinary E2 were significantly correlated with levels of lasting morning urinary and 24 h urinary Ca/Cr, serum T, 24 h urinary HOP respectively. CONCLUSION: Gusong-II could elevate the serum E2 levels of postmenopausal women, reduce the discharge of urinary Ca/Cr and HOP, inhibit the bone resorption. The rose of the serum E2 level might be correlated with the conversion of T into E2. |
| |
Keywords: | |
本文献已被 维普 等数据库收录! |
| 点击此处可从《中国中西医结合杂志》浏览原始摘要信息 |
| 点击此处可从《中国中西医结合杂志》下载免费的PDF全文 |
|