复方二矾浸液治疗手癣的临床与实验研究

为了验证复方二矾浸液治疗手癣的疗效及机理，本研究对复方二矾浸液治疗手癣进行了临床和实验研究。采用复方二矾浸液浸泡治疗手癣，同时，采用体外抗真菌试验及电镜方法，观察该浸液的临床疗效及抗菌效果。治疗组１３９例中痊愈１０４例，显效２１例，有效１０例，无效４例，愈显率８９．９％，与采用鹅掌风药液治疗的对照组愈显率比较，有显著性差异。体外抑制真菌试验表明，复方二矾浸液对红色毛癣菌，石膏样毛癣菌，石膏样小孢子

Clinical and Experimental Studies on Composite Divitriol Infusion in Treating Tinea Manum

To investigate the effect of Composite Divitriol Infusion (CDI) in treating tinea manum and studying its antimycotic action. Methods: CDI was used to treat 139 patients with tinea manum. The experimental study in vivo was done, scanning electron microscopy (SEM)was used to observe the therapeutical effect of CDI. Results: One hundred and four cases among the 139 patients were cured, 21 were markedly effective, 10 improved and 4 ineffective, the effective rate being 89. 9%. Between CDI group and the control group, there was a very significant difference (X2 >12. 84, P<0.005) . The antimycotic action of CDI was studied in vitro. Its minimum inhibitory concentrations(MIC) of CDI were about 0. 25% for Trichophyton rubrum, and 0, 5% for Trichophyton gypseum and Microsporum gypseum. Trichophyton rubrum immersed with CDI show that the mycelia became roughened, deformed and macroconidum became smaller under SEM. Conclusion:CDI is valuable in treating tinea manum.