柴胡桂枝汤对反复呼吸道感染患儿免疫球蛋白及IgG亚类的影响 |
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引用本文: | 李治淮,冯学斌,袭柱婷,刘凤.柴胡桂枝汤对反复呼吸道感染患儿免疫球蛋白及IgG亚类的影响[J].中国中西医结合杂志,1997,17(11):653-654. |
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作者姓名: | 李治淮 冯学斌 袭柱婷 刘凤 |
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作者单位: | 山东滨州医学院 |
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摘 要: | 目的:观察柴胡桂枝汤对反复呼吸道感染(RRTI)患儿免疫球蛋白(Ig)及IgG亚类的影响。方法:采用免疫扩散法和酶联免疫吸附法,检测了23例RRTI患儿柴胡枝汤治疗前后Ig和IgG亚类的含量,并与正常对照组比较,结果:RRTI患儿IgG,IgA,IgM浓度均显著低于正常对照组(P〈0.01),IgG亚类缺陷率60.9%,柴胡桂枝汤治疗临床总有效率95.6%,血清IgG浓度较治疗前明显升高(P〈0.
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关 键 词: | 柴胡桂枝汤 呼吸道感染 免疫球蛋白 IgG 儿童 |
Effect of Chaihu Guizhi Decoction on the Immunoglobulin and IgG Subgroup in Children with Recurrent Respiratory Tract Infection |
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Authors: | Z H Li X B Feng Z T Xi |
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Institution: | Binzhou Medical College, Shandong. |
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Abstract: | OBJECTIVE: To observe the effect of Chaihu Guizhi Decoction (CGD) on Immunoglobulin (Ig) and IgG subgroup in children with recurrent respiratory tract infection (RRTI). METHODS: Levels of Ig and IgG subgroup were measured in 23 cases of children with RRTI before and after treating with CGD, and compared with those in the control group. RESULTS: In RRTI group, the levels of IgG, IgA, IgM and IgG1 were lower than those of the control groups respectively (P < 0.01). The rate of IgG subgroup deficiency (ISD) was 60.9%. The effective rate of the CGD group was 95.6%. The IgG and IgG1 levels were increased after treatment as compared with before treatment (P < 0.05), and the ISD correcting rate being 71.4%. CONCLUSIONS: The hypoimmunofunction and IgG subgroup deficiency were important factors in RRTI pathogenesis. The CGD could improve the immunofunction and correct the IgG subgroup deficiency, and this effect might be one of the mechanism of CGD in treating RRTI. |
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Keywords: | Chaihu Guizhi Decoction recurrent respiratory tract infection immunoglobulin IgG subgroup |
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