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124例初诊骨髓增生异常综合征的骨髓象及骨髓活组织检查
引用本文:陈小剑,熊树民,黄婷.124例初诊骨髓增生异常综合征的骨髓象及骨髓活组织检查[J].现代诊断与治疗,2003,14(1):18-20.
作者姓名:陈小剑  熊树民  黄婷
作者单位:1. 温州医学院附属第二医院检验科,浙江,温州,325027
2. 上海第二医科大学附属瑞金医院,上海血液研究所,上海,200025
摘    要:目的 探讨初诊骨髓增生异常综合征 (MDS)病人的骨髓象及骨髓活组织检查结果。方法 对 12 4例确诊为MDS病人的骨髓象、临床表现、血液学检查结果及部分病人骨髓活组织检查结果进行分析。结果  12 4例病人均表现为贫血 ,部分还表现为全血细胞减少 ,骨髓象表现三系或二系或一系病态造血 ,骨髓活组织检查可见幼稚前期细胞异常定位(ALIP)。结论 诊断MDS的关键是病态造血 ,根据骨髓象特点排除其他相似疾病易诊断MDS ,同步进行骨髓活组织检查 ,能提高检出率。

关 键 词:骨髓增生异常综合征  骨髓象  骨髓活组织
文章编号:1001-8174(2003)01-0018-02
修稿时间:2002年4月8日

Myelograms and Bone Marrow Biopsies of 124 Cases of Myelodysplastic Syndrome Diagnosed Initialy
CHEN Xiao jian ,XIONG Shu min ,HUANG Ting.Myelograms and Bone Marrow Biopsies of 124 Cases of Myelodysplastic Syndrome Diagnosed Initialy[J].Modern Diagnosis & Treatment,2003,14(1):18-20.
Authors:CHEN Xiao jian  XIONG Shu min  HUANG Ting
Institution:CHEN Xiao jian 1,XIONG Shu min 2,HUANG Ting 2
Abstract:Objective To probe into the results of myelograms and bone marrow biopsies in patients with myelodysplastic syndrome(MDS) diagnosed initialy.Method The clinical manifestations,results of myelograms,hematological test and bone marrow biopsies in 124 cases of MDS were analyzed.Results There was anemia in all 124 cases.In a part of them,there were pancytopenia.Abnormal locolization of infantile cell prophase(ALIP)of bone marrow biopsies and abnormal hematopoiesis of myelogram in three systems(RBC,WBC,PLT) or two or one were found.Conclusions Abnormal hematopoiesis is the key to the diagnosis of MDS.According to the myelogram,it could be diagnosed easily after eliminating other similar diseases.Synchronous bone marrow biopsies could raise the detective ratio.
Keywords:Myelodysplastic syndrome  Myelogram  Bone marrow biopsy
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