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幽门螺杆菌感染非侵入性诊断方法的评价及研究进展
引用本文:吴亚男,邹全明,郭刚.幽门螺杆菌感染非侵入性诊断方法的评价及研究进展[J].医学研究生学报,2005,18(11):1045-1048.
作者姓名:吴亚男  邹全明  郭刚
作者单位:第三军医大学临床微生物及免疫学教研室重庆市生物制药工程技术研究中心,重庆,400038
基金项目:国家“九五”重点科技攻关资助项目(批准号:96-901-01-21);全军“九五”医药卫生科研基金资助项目(批准号:98D044)
摘    要:幽门螺杆菌(Hp)感染的非侵入性诊断方法以其无创优势倍受青睐.尿素呼吸实验和粪抗原被称为是Hp感染活动性检测;而血清和尿液抗体是检测Hp的标记物,并不能说明感染是否正在进行,所以被称之为被动检测.非侵入性检测被广泛推荐用于初次感染的诊断,选择合适的检测方法主要依赖于初筛感染的可能性、检测方法的特性及其性价比.作者对现在的非侵入性检测方法进行评价.

关 键 词:幽门螺杆菌  诊断技术  研究进展
文章编号:1008-8199(2005)11-1045-04
收稿时间:2005-06-13
修稿时间:2005-07-21

Method evaluation and research development of clinical non-invasive diagnosis of Helicobacter pylori infection
WU Ya-nan,ZOU Quan-ming,GUO Gang.Method evaluation and research development of clinical non-invasive diagnosis of Helicobacter pylori infection[J].Bulletin of Medical Postgraduate,2005,18(11):1045-1048.
Authors:WU Ya-nan  ZOU Quan-ming  GUO Gang
Institution:Laboratory of Clinic Microbiology and Immunology, Faculty of Medical Laboratory Sciences, the Third Military Medical University Chongqing Engineering Technology Research Center of Biopharma Centicals, Chongqing 400038, China
Abstract:Non-invasive diagnosis of Helicobacter pylori(H.pylori) infection is widely accepted for its non-invasiveness.Some non-invasive tests detect active infection e.g.the urea breath test and the stool antigen test and are called active tests.Other non-invasive tests are markers of exposure to H.pylori(e.g.serology or urine) but do not indicate whether active infection is ongoing and are called passive tests.Non-invasive tests are widely recommended in primary care settings and the choice of the appropriate test depends on the pre-test probability of infection,the characteristics of the test being used and its cost-effectiveness.The available non-invasive tests are reviewed in this article.
Keywords:Helicobacter pylori  Diagnose techniques  Research development
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