| 脑利钠肽对心力衰竭远期心脏事件的预测价值 |
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| 引用本文： | 王勉,胡咏梅,赵思勤,李秋,聂晓莉,吴涛,刘小蓉,张文勇.脑利钠肽对心力衰竭远期心脏事件的预测价值[J].临床心血管病杂志,2009,25(2). |
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| 作者姓名： | 王勉 胡咏梅 赵思勤 李秋 聂晓莉 吴涛 刘小蓉 张文勇 |
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| 作者单位： | 成都市第二人民医院心内科,成都,610017 |
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| 摘 要： | 目的:研究血浆脑利钠肽(BNP)对慢性心力衰竭(心衰)患者远期心脏事件的预测价值.方法:入选134例心衰患者,双抗体夹心免疫荧光法测定血浆BNP浓度,记录发生的心脏事件.结果:134例中随访资料完整130例,随访时间平均(708±220)d.130例中发生心脏事件者44例(心脏事件组),未发生心脏事件者86例(非心脏事件组),心脏事件组左室舒张末期内径、心胸比率、BNP均较非心脏事件组显著升高(均P<0.01).多元logistic回归分析显示,BNP为心衰患者远期心脏事件独立的预测因子.BNP预测心源性死亡ROC曲线下面积为0.846.BNP取值702.5 ng/L预测心源性死亡的敏感度和特异度达最高.血浆BNP≤702.5 ng/L患者生存率高于BNP>702.5 ng/L者(P<0.05). 结论:BNP是影响慢性心衰患者远期心脏事件的独立预测因素.
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| 关 键 词： | 心力衰竭 充血性 利钠肽 脑 预后 |
Long prognostic value of B-natriuretic peptide on admission in patients with chronic heart failure |
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| WANG Mian,HU Yongmei,ZHAO Siqin,LI Qiu,NIE Xiaoli,WU Tao,LIU Xiaorong,ZHANG Wenyong.Long prognostic value of B-natriuretic peptide on admission in patients with chronic heart failure[J].Journal of Clinical Cardiology,2009,25(2). |
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| Authors: | WANG Mian HU Yongmei ZHAO Siqin LI Qiu NIE Xiaoli WU Tao LIU Xiaorong ZHANG Wenyong |
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| Abstract: | Objective:To evaluate the long prognostic value of plasma B-natriuretic peptide(BNP) on predicting cardiovascular events after hospital discharge in patients with chronic heart failure(CHF).Method:Patients with CHF(n=134) were included in this study.Plasma BNP level was obtained by a rapid immunofluorescence assay in all patients.Left ventricular end diastolic diameter(LVEDD) and cardiothoracic ratio(CRT) were performed within 24 h before or after catheterization.All CHF patients were received conventional ... |
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| Keywords: | heart failure congestive natriuretic peptide brain prognosis |
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