| 新型药物Salazotyrin对类风湿性关节炎患者的疗效观察 |
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| 引用本文： | 宁建新.新型药物Salazotyrin对类风湿性关节炎患者的疗效观察[J].中国现代医生,2011,49(16):49-50. |
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| 作者姓名： | 宁建新 |
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| 作者单位： | 浙江省江山市中医院骨科,浙江江山,424100 |
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| 摘 要： | 目的观察肿瘤坏死因子抑制剂Salazotyrin治疗类风湿性关节炎（rheumatoid arthritis，RA）的治疗效果及对人体的安全性。方法97例RA患者随机分为两组，对照组57例给予传统药物氨甲蝶呤和硫酸羟氯喹；治疗组40例应用Salazotyrin进行为期3个月的治疗。结果治疗组总有效率（92．5％）显著高于对照组（71．9％）（P〈0．05），在关节肿胀数、关节肿胀指数、晨僵时间和关节压痛指数等方面均与用药前有显著差异（P〈0．05），且该药与传统药物所产生的副反应无显著差异。结论Salazotyrin治疗RA疗效明显优于传统的氨甲蝶呤和硫酸羟氯喹，且不良反应少而轻微，安全性好。
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| 关 键 词： | 类风湿性关节炎 Salazotyrin 抑制剂 |
Clinical Study of Rheumatoid Arthritis Treated by A New Drug Salazotyrin |
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| Authors: | NING Jianxin |
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| Institution: | NING Jianxin Department of Drthopaedics,Zhejiang Province Jiangshan Traditional Chinese Medicine Hospital,Jiangshan 424100,China |
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| Abstract: | Objective To observe the effectiveness and safety in the treatment of rheumatoid arthritis(RA) with a antagonist for tumor necrosis factor,Salazotyrin.Methods We randomly divided 97 RA patients into 2 groups:the control group(57 RA patients) was given hydroxychloroquine and methotrexate sulfuric acid for 3 months;the treatment group(40 patients) was treated by Salazotyrin for the same period.Results The total effectiveness rate of the treatment group(92.5%) was significantly higher than that of control grou... |
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| Keywords: | Rheumatoid arthritis Salazotyrin Antagonist |
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