老年2型糖尿病患者骨量改变与动脉硬化的相关性研究

目的通过对60岁以上2型糖尿病患者骨密度与颈动脉内中膜厚度及斑块关系的分析,探讨骨量减低与动脉硬化的关系。方法对123例老年2型糖尿病患者行双能X线骨密度仪测定腰椎、髋部的骨密度,并行颈动脉超声检测颈动脉内中膜厚度及斑块,根据骨密度分为骨量正常及骨量减低组,并对它们进行相关分析。结果老年2型糖尿病患者,骨量减低组动脉动脉硬化的发生率为60.8%,高于骨量正常组的41.7%,差异有统计学意义（P〈0.05）。结论骨量改变与动脉硬化有密切的关系,是否可作为骨量变化敏感的预测因子有待扩大病例数作进一步观察。

Correlation of Bone Mass Changes on Elderly Patients with Type 2 Diabetes and Arteriosclerosis

[Objective] To investigate the correlation of bone mineral density（BMD） and atherosclerosis through analysis on bone mineral density of type 2 diabetes patients over 60 years and intima-media thickness of carotid artery with plaque. [Methods]A total of 123 elderly patients with type 2 diabetes were recruited. dual energy X ray absorptiometry was adopted to detect bone mineral density of lumbar spine and hip. Carotid ultrasonic examination was applied to detect intima-media thickness of carotid artery and plaque. The patients were divided into normal bone mass group and bone mass reducing group for correlation analysis.[Results]The incidence of atherosclerosis among elderly patients with type 2 diabetes of bone mass reducing group was 60.8% which was higher than 41.7% of patients of normal bone mass group,the difference was significant （P〈0.05）.[Conclusion]Bone mass changes relates closely with the arteriosclerosis,but whether it can be taken as sensitive predictor of bone mass changes needs to be further studied with expanding number of cases.