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Expression of interferon gamma by a highly virulent strain of Newcastle disease virus decreases its pathogenicity in chickens
Institution:1. Southeast Poultry Research Laboratory USDA ARS, 934 College Station Rd., Athens, GA 30605, USA;2. Department of Veterinary Pathology, College of Veterinary Medicine, University of Georgia, Athens, GA 30605, USA;3. Animal Infectious Disease Laboratory, School of Veterinary Medicine, Yangzhou University, Yangzhou, PR China;1. College of Life Science, Nanjing Agricultural University, Weigang 1, Nanjing, Jiangsu 210095, PR China;2. College of Veterinary Medicine, Nanjing Agricultural University, Weigang 1, Nanjing, Jiangsu 210095, PR China;1. Graduate Institute of Animal Vaccine Technology, College of Veterinary Medicine, National Pingtung University of Science and Technology, 912 Pingtung, Taiwan;2. Department of Veterinary Medicine, College of Veterinary Medicine, National Pingtung University of Science and Technology, 912 Pingtung, Taiwan;3. Institute of Molecular Biology, National Chung Hsing University, 40227 Taichung, Taiwan;4. Department of Life Science, National Taiwan Normal University, Taipei 11677, Taiwan;1. CIRAD, UMR ASTRE, F-34398 Montpellier, France;2. CIRAD, UMR ASTRE, F-97170 Petit-Bourg, Guadeloupe, France;3. INRA, UMR1309 ASTRE, F-34398 Montpellier, France;2. Department of Pathobiology, School of Veterinary Medicine, Shiraz University, Shiraz, Iran;3. Department of Avian Medicine, School of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran
Abstract:
Keywords:Newcastle disease virus  Chicken IFN-γ  Pathogenesis  Immunopathogenesis  Cytokine storm  Reverse genetics  NDV"}  {"#name":"keyword"  "$":{"id":"kwrd0045"}  "$$":[{"#name":"text"  "_":"Newcastle disease virus  ND"}  {"#name":"keyword"  "$":{"id":"kwrd0055"}  "$$":[{"#name":"text"  "_":"Newcastle disease  IFN-γ"}  {"#name":"keyword"  "$":{"id":"kwrd0065"}  "$$":[{"#name":"text"  "_":"interferon gamma  IFN-α"}  {"#name":"keyword"  "$":{"id":"kwrd0075"}  "$$":[{"#name":"text"  "_":"interferon alpha  IFN-β"}  {"#name":"keyword"  "$":{"id":"kwrd0085"}  "$$":[{"#name":"text"  "_":"interferon beta  IL-6"}  {"#name":"keyword"  "$":{"id":"kwrd0095"}  "$$":[{"#name":"text"  "_":"interleukin six  SAA1"}  {"#name":"keyword"  "$":{"id":"kwrd0105"}  "$$":[{"#name":"text"  "_":"serum amyloid protein A  NO"}  {"#name":"keyword"  "$":{"id":"kwrd0115"}  "$$":[{"#name":"text"  "_":"nitric oxide  iNOS"}  {"#name":"keyword"  "$":{"id":"kwrd0125"}  "$$":[{"#name":"text"  "_":"inducible nitric oxide synthetase  ICPI"}  {"#name":"keyword"  "$":{"id":"kwrd0135"}  "$$":[{"#name":"text"  "_":"intra cerebral pathogenicity index  MALT"}  {"#name":"keyword"  "$":{"id":"kwrd0145"}  "$$":[{"#name":"text"  "_":"mucosa associated lymphoid tissue  GFP"}  {"#name":"keyword"  "$":{"id":"kwrd0155"}  "$$":[{"#name":"text"  "_":"green fluorescent protein  ISRGs"}  {"#name":"keyword"  "$":{"id":"kwrd0165"}  "$$":[{"#name":"text"  "_":"interferon-stimulated response genes
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