Portal vein thrombosis in a patient with hepatitis C virus-related cirrhosis complicated with antiphospholipid syndrome |
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Authors: | Yohei Kida Etsuko Maeshima Yoichi Yamada |
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Institution: | (1) Department of Internal Medicine, Kainan Municipal Hospital, 1272-3 Hikata, Kainan 642-0002, Japan;(2) Department of Health and Sport Management, Osaka University of Health and Sport Sciences, Kumatori, Japan |
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Abstract: | We report a rare case of portal vein thrombosis (PVT) associated with antiphospholipid syndrome (APS) and hepatitis C virus-related
cirrhosis. A 59-year-old woman with hepatitis C virus (HCV) infection was admitted because of coma. The blood test showed
a typically cirrhosis pattern including an elevated serum ammonia level. Abdominal computed tomography showed liver cirrhosis
and thrombus in the right branch of the portal vein. To elucidate the cause of PVT, antiphospholipid antibodies were examined.
Both IgG anti-cardiolipin antibody (ELISA) and IgG anti-cardiolipin-β2 -glycoprotein I complex antibody (ELISA) were positive.
When PVT is detected in a patient with cirrhosis, it might be necessary to examine antiphospholipid antibodies to clarify
the cause of PVT. |
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Keywords: | Portal vein thrombosis Antiphospholipid syndrome Hepatitis C virus Cirrhosis |
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