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正交试验优选紫草凝胶提取工艺
引用本文:刘万华,刘洁.正交试验优选紫草凝胶提取工艺[J].中国药房,2011(3):234-235.
作者姓名:刘万华  刘洁
作者单位:天津医科大学总医院,天津市300052
摘    要:目的:优选紫草凝胶中紫草的提取工艺。方法:以乙醇浓度、乙醇用量、浸出时间为考察因素,以左旋紫草素含量为评价指标,采用正交试验优选紫草凝胶中紫草的提取工艺。结果:优选的工艺为用16倍药材量的95%乙醇提取3h,左旋紫草素含量为5.672mg·g-1药材。结论:该工艺稳定、可行,可用于紫草凝胶中紫草的提取。

关 键 词:提取  正交试验  左旋紫草素

Optimization of the Extraction Technology of Radix Arnebiae Gel by Orthogonal Experiment
LIU Wan-hua,LIU Jie.Optimization of the Extraction Technology of Radix Arnebiae Gel by Orthogonal Experiment[J].China Pharmacy,2011(3):234-235.
Authors:LIU Wan-hua  LIU Jie
Institution:(Tianjin Medical University General Hospital,Tianjin 300052,China)
Abstract:OBJECTIVE:To optimize the extraction technology of Radix Arnebiae gel.METHODS:Orthogonal design was carried out to optimize the extraction technology of Radix Arnebiae gel using the concentration and amount of ethanol and extraction time as factors and using the content of shikonin as index.RESULTS:The optimal extracting technology was as follows:16-folds 95% alcohol for 3 hours.The content of L-shikonin was 5.672 mg·g-1.CONCLUSION:The extraction of L-shikonin is stable and feasible for the extraction of Radix Arnebiae from Radix Arnebiae gel.
Keywords:Extraction  Orthogonal experiment  L-shikonin
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