| 2种新辅助化疗方案治疗乳腺癌的成本-效果分析 |
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| 引用本文： | 杜书章,张晓坚,岳晓红. 2种新辅助化疗方案治疗乳腺癌的成本-效果分析[J]. 中国药房, 2011, 0(12): 1109-1110 |
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| 作者姓名： | 杜书章 张晓坚 岳晓红 |
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| 作者单位： | 郑州大学第一附属医院,郑州市450052 |
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| 摘 要： | 目的:比较2种新辅助化疗方案治疗乳腺癌的经济学效果。方法:80例乳腺癌患者随机均分为CTF组(环磷酰胺+吡柔比星+5-氟尿嘧啶)和TT组(吡柔比星+紫衫醇)组,新辅助化疗3～4周为1个周期,所有患者在完成2个周期新辅助化疗后进行成本-效果分析。结果:CTF组与TT组的成本分别为2850.00元、5145.00元,总有效率分别为52.5%、82.5%(P<0.05),成本-效果比分别为5428.57、6236.36。结论:CTF组的治疗方案为优选方案。
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| 关 键 词： | 乳腺肿瘤 新辅助化疗 环磷酰胺 吡柔比星 5-氟尿嘧啶 紫衫醇 |
Cost-effectiveness Analysis of 2 Kinds of Neoadjuvant Chemotherapy Schemes for Breast Cancer |
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| Affiliation: | DU Shu-zhang, ZHANG Xiao-jian, YUE Xaio-hong(The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China) |
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| Abstract: | To explore the cost-effectiveness of 2 kinds of neoadjuvant chemotherapy schemes for breast cancer. METHODS： 80 cases of breast cancer were randomly divided into 2 groups, i.e. CTF group （cyclophosphamide＋pirarubicin＋5-fluorouracil） and TT group （pirarubicin＋paclitaxel） ; One treatment course lasted for 3-4 weeks. Cost-effectiveness analysis of 2 kinds of neoadjuvant chemotherapy schemes were conducted after 2 treatment courses. RESULTS： The costs of CTF group and TT group were 2 850.00 yuan and 5 145.00 yuan, respectively, and total effective rates were 52.5% and 82.5% （P（0.05）. THe cost-effectiveness ratios were 5 428.57 and 6 236.36. CONCLUSION： Chemotherapy scheme of CTF group is optimal. |
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| Keywords: | Breast tumor Neoadjuvant chemotherapy Cyclophosphamide Pirarubicin 5-fluorouracil Paclitaxel |
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